Calpain inhibition improves erectile function in diabetic mice via upregulating endothelial nitric oxide synthase expression and reducing apoptosis

Calpain inhibition improves erectile function in diabetic mice via upregulating endothelial nitric oxide synthase expression and reducing apoptosis

Calpain activation contributes to hyperglycemia-induced endothelial dysfunction and apoptosis. This study was designed to investigate the role of calpain inhibition in improving diabetic erectile dysfunction (ED) in mice. Thirty-eight-week-old male C57BL/6J mice were divided into three groups: (1) n...

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Bibliographic Details
Main Authors: Hao Li, Li-Ping Chen, Tao Wang, Shao-Gang Wang, Ji-Hong Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Asian Journal of Andrology
Subjects:
apoptosis; calpain; diabetes; endothelial nitric oxide synthase; erectile dysfunction
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2018;volume=20;issue=4;spage=342;epage=348;aulast=Li

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