Bevacizumab Arrests Osteoarthritis Progression in a Rabbit Model: A Dose-Escalation Study

Cartilage neoangiogenesis holds a prominent role in osteoarthritis (OA) pathogenesis. This study aimed to assess the efficacy bevacizumab, an antibody against vascular endothelial growth factor and inhibitor of angiogenesis, in a rabbit OA model. Animals were divided into four groups: one receiving...

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Bibliographic Details
Main Authors: Gianluca Vadalà, Luca Ambrosio, Caterina Cattani, Roberta Bernardini, Antonino Giacalone, Rocco Papalia, Vincenzo Denaro
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/13/2825