Diabetic ketoacidosis after the treatment of anaphylaxis
Anaphylaxis is a rapidly progressive potentially lethal condition, and epinephrine is the most crucial medication in its treatment. In this study, we present a case of diabetic ketoacidosis in a young woman that was precipitated by the administration of epinephrine to treat anaphylaxis. This patient...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Bioscientifica
2022-08-01
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| Series: | Endocrinology, Diabetes & Metabolism Case Reports |
| Online Access: | https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0171.xml |
| _version_ | 1798037008744972288 |
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| author | Daniel S Brenner Keith Kleinman Amy Manzo Melania M Bembea David W Cooke |
| author_facet | Daniel S Brenner Keith Kleinman Amy Manzo Melania M Bembea David W Cooke |
| author_sort | Daniel S Brenner |
| collection | DOAJ |
| description | Anaphylaxis is a rapidly progressive potentially lethal condition, and epinephrine is the most crucial medication in its treatment. In this study, we present a case of diabetic ketoacidosis in a young woman that was precipitated by the administration of epinephrine to treat anaphylaxis. This patient had diabetes mellitus and poor glycemic control and developed ketoacidosis despite having evidence of ongoing endogenous insulin production and having been treated with exogenous long-acting insulin less than 24 h prior to the event. This is a rare, serious, adverse side effect of life-saving medication. This report demonstrates that the risk of diabetic ketoacidosis should be considered when administering epinephrine to patients with diabetes, even in the absence of complete insulin deficiency. |
| first_indexed | 2024-04-11T21:20:49Z |
| format | Article |
| id | doaj.art-e9f1b2610055499f9c23bca107cabfa9 |
| institution | Directory Open Access Journal |
| issn | 2052-0573 |
| language | English |
| last_indexed | 2024-04-11T21:20:49Z |
| publishDate | 2022-08-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism Case Reports |
| spelling | doaj.art-e9f1b2610055499f9c23bca107cabfa92022-12-22T04:02:38ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732022-08-01111410.1530/EDM-21-0171Diabetic ketoacidosis after the treatment of anaphylaxisDaniel S Brenner0Keith Kleinman1Amy Manzo2Melania M Bembea3David W Cooke4Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USADivision of Pediatric Emergency Medicine, Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland, USADepartment of Pediatric Anesthesiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USADepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USADivision of Pediatric Endocrinology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAAnaphylaxis is a rapidly progressive potentially lethal condition, and epinephrine is the most crucial medication in its treatment. In this study, we present a case of diabetic ketoacidosis in a young woman that was precipitated by the administration of epinephrine to treat anaphylaxis. This patient had diabetes mellitus and poor glycemic control and developed ketoacidosis despite having evidence of ongoing endogenous insulin production and having been treated with exogenous long-acting insulin less than 24 h prior to the event. This is a rare, serious, adverse side effect of life-saving medication. This report demonstrates that the risk of diabetic ketoacidosis should be considered when administering epinephrine to patients with diabetes, even in the absence of complete insulin deficiency.https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0171.xml |
| spellingShingle | Daniel S Brenner Keith Kleinman Amy Manzo Melania M Bembea David W Cooke Diabetic ketoacidosis after the treatment of anaphylaxis Endocrinology, Diabetes & Metabolism Case Reports |
| title | Diabetic ketoacidosis after the treatment of anaphylaxis |
| title_full | Diabetic ketoacidosis after the treatment of anaphylaxis |
| title_fullStr | Diabetic ketoacidosis after the treatment of anaphylaxis |
| title_full_unstemmed | Diabetic ketoacidosis after the treatment of anaphylaxis |
| title_short | Diabetic ketoacidosis after the treatment of anaphylaxis |
| title_sort | diabetic ketoacidosis after the treatment of anaphylaxis |
| url | https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM21-0171.xml |
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