Ultrastructural comparison of dendritic spine morphology preserved with cryo and chemical fixation

Ultrastructural comparison of dendritic spine morphology preserved with cryo and chemical fixation

Previously, we showed that cryo fixation of adult mouse brain tissue gave a truer representation of brain ultrastructure in comparison with a standard chemical fixation method (Korogod et al., 2015). Extracellular space matched physiological measurements, there were larger numbers of docked vesicles...

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Bibliographic Details
Main Authors: Hiromi Tamada, Jerome Blanc, Natalya Korogod, Carl CH Petersen, Graham W Knott
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
cryo fixation
dendritic spine
electron microscopy
ultrastructure
dendrite
Online Access:https://elifesciences.org/articles/56384

Internet

https://elifesciences.org/articles/56384

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