Photoacoustic mediated multifunctional tumor antigen trapping nanoparticles inhibit the recurrence and metastasis of ovarian cancer by enhancing tumor immunogenicity

Photoacoustic mediated multifunctional tumor antigen trapping nanoparticles inhibit the recurrence and metastasis of ovarian cancer by enhancing tumor immunogenicity

Abstract The hypoimmunogenicity of tumors is one of the main bottlenecks of cancer immunotherapy. Enhancing tumor immunogenicity can improve the efficacy of tumor immunotherapy by increasing antigen exposure and presentation, and establishing an inflammatory microenvironment. Here, a multifunctional...

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Bibliographic Details
Main Authors: Xiaowen Zhong, Chenyang Li, Guangzong Zhao, Mengmeng Li, Shuning Chen, Yang Cao, Qi Wang, Jiangchuan Sun, Shenyin Zhu, Shufang Chang
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Nanobiotechnology
Subjects:
Antigen capture
Immunogenic cell death
Tumor immunotherapy
Photodynamic therapy
Photothermal therapy
Photoacoustic imaging
Online Access:https://doi.org/10.1186/s12951-022-01682-5

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