Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy
Neurological and psychiatric conditions frequently overlap in neuro-oncology. This overlapping negatively affects patients’ quality of life and decreases the ability of providers to manage specific symptoms by therapy modulation, especially when psychopharmacotherapy needs to be prescribed. We descr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2016-06-01
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| Series: | Case Reports in Neurology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/446643 |
| _version_ | 1811308968438398976 |
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| author | Andrea Botturi Antonio Silvani Gabriella Pravettoni Riccardo Augusto Paoli Claudio Lucchiari |
| author_facet | Andrea Botturi Antonio Silvani Gabriella Pravettoni Riccardo Augusto Paoli Claudio Lucchiari |
| author_sort | Andrea Botturi |
| collection | DOAJ |
| description | Neurological and psychiatric conditions frequently overlap in neuro-oncology. This overlapping negatively affects patients’ quality of life and decreases the ability of providers to manage specific symptoms by therapy modulation, especially when psychopharmacotherapy needs to be prescribed. We describe here a patient with recurrent brain tumor, symptomatic epilepsy and depression who developed Pisa syndrome and parkinsonism after several months of valproic acid use. An accurate recognition of symptoms and treatment side effect allowed an appropriate clinical approach so as to rapidly improve both movement disorder and depression without increasing the risk of developing seizure. This has improved the autonomy and quality of life in a patient with poor prognosis. |
| first_indexed | 2024-04-13T09:32:48Z |
| format | Article |
| id | doaj.art-e9f87b8dd65b412a9aa62fbb44c93486 |
| institution | Directory Open Access Journal |
| issn | 1662-680X |
| language | English |
| last_indexed | 2024-04-13T09:32:48Z |
| publishDate | 2016-06-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Neurology |
| spelling | doaj.art-e9f87b8dd65b412a9aa62fbb44c934862022-12-22T02:52:11ZengKarger PublishersCase Reports in Neurology1662-680X2016-06-018211511910.1159/000446643446643Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and EpilepsyAndrea BotturiAntonio SilvaniGabriella PravettoniRiccardo Augusto PaoliClaudio LucchiariNeurological and psychiatric conditions frequently overlap in neuro-oncology. This overlapping negatively affects patients’ quality of life and decreases the ability of providers to manage specific symptoms by therapy modulation, especially when psychopharmacotherapy needs to be prescribed. We describe here a patient with recurrent brain tumor, symptomatic epilepsy and depression who developed Pisa syndrome and parkinsonism after several months of valproic acid use. An accurate recognition of symptoms and treatment side effect allowed an appropriate clinical approach so as to rapidly improve both movement disorder and depression without increasing the risk of developing seizure. This has improved the autonomy and quality of life in a patient with poor prognosis.http://www.karger.com/Article/FullText/446643EpilepsyParkinsonismValproic acidNeuro-oncologyDepression |
| spellingShingle | Andrea Botturi Antonio Silvani Gabriella Pravettoni Riccardo Augusto Paoli Claudio Lucchiari Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy Case Reports in Neurology Epilepsy Parkinsonism Valproic acid Neuro-oncology Depression |
| title | Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy |
| title_full | Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy |
| title_fullStr | Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy |
| title_full_unstemmed | Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy |
| title_short | Reversible Valproate Induced Pisa Syndrome and Parkinsonism in a Neuro-Oncology Patient with Depression and Epilepsy |
| title_sort | reversible valproate induced pisa syndrome and parkinsonism in a neuro oncology patient with depression and epilepsy |
| topic | Epilepsy Parkinsonism Valproic acid Neuro-oncology Depression |
| url | http://www.karger.com/Article/FullText/446643 |
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