Molecular characterization of the PhiKo endolysin from Thermus thermophilus HB27 bacteriophage phiKo and its cryptic lytic peptide RAP-29

Molecular characterization of the PhiKo endolysin from Thermus thermophilus HB27 bacteriophage phiKo and its cryptic lytic peptide RAP-29

IntroductionIn the era of increasing bacterial resistance to antibiotics, new bactericidal substances are sought, and lysins derived from extremophilic organisms have the undoubted advantage of being stable under harsh environmental conditions. The PhiKo endolysin is derived from the phiKo bacteriop...

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Bibliographic Details
Main Authors: Monika Szadkowska, Aleksandra Maria Kocot, Daria Sowik, Dariusz Wyrzykowski, Elzbieta Jankowska, Lukasz Pawel Kozlowski, Joanna Makowska, Magdalena Plotka
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
bacteriophage
thermostable endolysin
antimicrobial peptide
lysin
extremophile
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1303794/full

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