ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells[S]

ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells[S]

Hepatic stellate cell (HSC) activation is a critical step in the development of chronic liver disease. During activation, HSCs lose their lipid droplets (LDs) containing triacylglycerol (TAG), cholesteryl esters (CEs), and retinyl esters (REs). Here we aimed to investigate which enzymes are involved...

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Bibliographic Details
Main Authors: Maidina Tuohetahuntila, Martijn R. Molenaar, Bart Spee, Jos F. Brouwers, Martin Houweling, Arie B. Vaandrager, J. Bernd Helms
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Journal of Lipid Research
Subjects:
vitamin A
lipase
lipolysis and fatty acid metabolism
lipid droplets
lipidomics
heavy isotope labeling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520351543

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