A gene prognostic index from cellular senescence predicting metastasis and radioresistance for prostate cancer

A gene prognostic index from cellular senescence predicting metastasis and radioresistance for prostate cancer

Abstract Background Senescent cells have been identified in the aging prostate, and the senescence-associated secretory phenotype might be linked to prostate cancer (PCa). Thus, we established a cellular senescence-related gene prognostic index (CSGPI) to predict metastasis and radioresistance in PC...

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Bibliographic Details
Main Authors: Dechao Feng, Dengxiong Li, Xu Shi, Qiao Xiong, Facai Zhang, Qiang Wei, Lu Yang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Translational Medicine
Subjects:
Cellular senescence
Prognostic index
Prostate cancer
Tumor immune microenvironment
Metastasis-free survival
Radioresistance
Online Access:https://doi.org/10.1186/s12967-022-03459-8

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