9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one
Chemoselective reduction of the corresponding 9-nitro precursor by catalytic transfer hydrogenation afforded the title compound, a new 9-amino derivative of the antitumor alkaloid Luotonin A, in good yield. The structure of the compound was established by means of 1D and 2D 1H-NMR and 13C-NMR spectr...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-03-01
|
| Series: | Molbank |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1422-8599/2019/1/M1050 |
| _version_ | 1818840587963465728 |
|---|---|
| author | Eugen Schneider Norbert Haider |
| author_facet | Eugen Schneider Norbert Haider |
| author_sort | Eugen Schneider |
| collection | DOAJ |
| description | Chemoselective reduction of the corresponding 9-nitro precursor by catalytic transfer hydrogenation afforded the title compound, a new 9-amino derivative of the antitumor alkaloid Luotonin A, in good yield. The structure of the compound was established by means of 1D and 2D 1H-NMR and 13C-NMR spectroscopy as well as by EI-MS and high-resolution ESI-MS. |
| first_indexed | 2024-12-19T04:12:34Z |
| format | Article |
| id | doaj.art-ea0443f7a9034902bdd3919b82f73926 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-12-19T04:12:34Z |
| publishDate | 2019-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-ea0443f7a9034902bdd3919b82f739262022-12-21T20:36:23ZengMDPI AGMolbank1422-85992019-03-0120191M105010.3390/M1050M10509-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-oneEugen Schneider0Norbert Haider1Department of Pharmaceutical Chemistry, University of Vienna, Althanstraße 14, A-1090 Vienna, AustriaDepartment of Pharmaceutical Chemistry, University of Vienna, Althanstraße 14, A-1090 Vienna, AustriaChemoselective reduction of the corresponding 9-nitro precursor by catalytic transfer hydrogenation afforded the title compound, a new 9-amino derivative of the antitumor alkaloid Luotonin A, in good yield. The structure of the compound was established by means of 1D and 2D 1H-NMR and 13C-NMR spectroscopy as well as by EI-MS and high-resolution ESI-MS.http://www.mdpi.com/1422-8599/2019/1/M1050Luotonin Anitro group reductioncatalytic transfer hydrogenation |
| spellingShingle | Eugen Schneider Norbert Haider 9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one Molbank Luotonin A nitro group reduction catalytic transfer hydrogenation |
| title | 9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one |
| title_full | 9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one |
| title_fullStr | 9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one |
| title_full_unstemmed | 9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one |
| title_short | 9-Aminoquino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one |
| title_sort | 9 aminoquino 2 3 3 4 pyrrolo 2 1 b quinazolin 11 13h one |
| topic | Luotonin A nitro group reduction catalytic transfer hydrogenation |
| url | http://www.mdpi.com/1422-8599/2019/1/M1050 |
| work_keys_str_mv | AT eugenschneider 9aminoquino2334pyrrolo21bquinazolin1113hone AT norberthaider 9aminoquino2334pyrrolo21bquinazolin1113hone |