Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia
Objectives: In this study, we hypothesized that dietary salt and potassium intake may be related with blood pressure, kidney damage and perinatal outcome in pregnants with preeclampsia (PE). Methods: In total, 200 women (50 control women with healthy pregnancy, 150 women with PE) were recruited for...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-01-01
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| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2016.1239734 |
| _version_ | 1797681617803673600 |
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| author | Zehra Vural Yılmaz Elif Akkaş Gülenay Gençosmanoğlu Türkmen Özgür Kara Aykan Yücel Dilek Uygur |
| author_facet | Zehra Vural Yılmaz Elif Akkaş Gülenay Gençosmanoğlu Türkmen Özgür Kara Aykan Yücel Dilek Uygur |
| author_sort | Zehra Vural Yılmaz |
| collection | DOAJ |
| description | Objectives: In this study, we hypothesized that dietary salt and potassium intake may be related with blood pressure, kidney damage and perinatal outcome in pregnants with preeclampsia (PE). Methods: In total, 200 women (50 control women with healthy pregnancy, 150 women with PE) were recruited for the study. Daily salt and potassium intake was estimated based on calculation of 24-hour urinary sodium U[Na+] and potassium U[K+] excretion. U[Na+]/[K+] was calculated by dividing U[Na+] by U[K+]. At the end of the measurements, the pregnant women with PE (n=150) were divided into tertiles according to U[Na+]/[K+]: low Na/K group (n=50, mean U[Na+]/[K+]: 1,04±0,32), medium Na/K group (n=50, mean U[Na+]/[K+]: 2,49± 0,54), high Na/K group (n=50, mean U[Na+]/[K+]: 6,62±3,41). Results: The mean SBP and DBP levels were significantly lower in low Na/K group compared with medium or high Na/K groups (p=0.024, p=0.0002; respectively). Serum creatinine was significantly lower in low Na/K group than high Na/K group (p=0.025). Frequency of severe preeclampsia is lower in low Na/K group than medium or high Na/K groups (p=0.002, p=0.0001; respectively). Birth weight and gestational age at birth were higher in low Na/K group compared with high Na/K group (p=0.045, p=0.0002; respectively). After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake. |
| first_indexed | 2024-03-11T23:47:29Z |
| format | Article |
| id | doaj.art-ea0761e4f9ec4e95a93a43e4d87f7520 |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:47:29Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-ea0761e4f9ec4e95a93a43e4d87f75202023-09-19T09:24:41ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652017-01-01361778310.1080/10641955.2016.12397341239734Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsiaZehra Vural Yılmaz0Elif Akkaş1Gülenay Gençosmanoğlu Türkmen2Özgür Kara3Aykan Yücel4Dilek Uygur5Zekai Tahir Burak Women’s Health Education and Training HospitalDr. Sami Ulus Women’s and Children’s Health Training and Research HospitalZekai Tahir Burak Women’s Health Education and Training HospitalZekai Tahir Burak Women’s Health Education and Training HospitalZekai Tahir Burak Women’s Health Education and Training HospitalZekai Tahir Burak Women’s Health Education and Training HospitalObjectives: In this study, we hypothesized that dietary salt and potassium intake may be related with blood pressure, kidney damage and perinatal outcome in pregnants with preeclampsia (PE). Methods: In total, 200 women (50 control women with healthy pregnancy, 150 women with PE) were recruited for the study. Daily salt and potassium intake was estimated based on calculation of 24-hour urinary sodium U[Na+] and potassium U[K+] excretion. U[Na+]/[K+] was calculated by dividing U[Na+] by U[K+]. At the end of the measurements, the pregnant women with PE (n=150) were divided into tertiles according to U[Na+]/[K+]: low Na/K group (n=50, mean U[Na+]/[K+]: 1,04±0,32), medium Na/K group (n=50, mean U[Na+]/[K+]: 2,49± 0,54), high Na/K group (n=50, mean U[Na+]/[K+]: 6,62±3,41). Results: The mean SBP and DBP levels were significantly lower in low Na/K group compared with medium or high Na/K groups (p=0.024, p=0.0002; respectively). Serum creatinine was significantly lower in low Na/K group than high Na/K group (p=0.025). Frequency of severe preeclampsia is lower in low Na/K group than medium or high Na/K groups (p=0.002, p=0.0001; respectively). Birth weight and gestational age at birth were higher in low Na/K group compared with high Na/K group (p=0.045, p=0.0002; respectively). After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake.http://dx.doi.org/10.1080/10641955.2016.1239734preeclampsiaoutcomesodium intakepotassium intake |
| spellingShingle | Zehra Vural Yılmaz Elif Akkaş Gülenay Gençosmanoğlu Türkmen Özgür Kara Aykan Yücel Dilek Uygur Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia Hypertension in Pregnancy preeclampsia outcome sodium intake potassium intake |
| title | Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia |
| title_full | Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia |
| title_fullStr | Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia |
| title_full_unstemmed | Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia |
| title_short | Dietary sodium and potassium intake were associated with hypertension, kidney damage and adverse perinatal outcome in pregnant women with preeclampsia |
| title_sort | dietary sodium and potassium intake were associated with hypertension kidney damage and adverse perinatal outcome in pregnant women with preeclampsia |
| topic | preeclampsia outcome sodium intake potassium intake |
| url | http://dx.doi.org/10.1080/10641955.2016.1239734 |
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