MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia
Case summary A 2-year-old neutered female domestic shorthair cat presented with a history of hypodipsia, recurrent hypernatraemia, pelvic limb ataxia and tremor. The serum arginine vasopressin level was low for the serum osmolality. MRI of the brain revealed a failure of separation of the cerebrum,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2018-09-01
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| Series: | Journal of Feline Medicine and Surgery Open Reports |
| Online Access: | https://doi.org/10.1177/2055116918801602 |
| _version_ | 1818146394886635520 |
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| author | Genya Shimbo Michihito Tagawa Masashi Yanagawa Kazuro Miyahara |
| author_facet | Genya Shimbo Michihito Tagawa Masashi Yanagawa Kazuro Miyahara |
| author_sort | Genya Shimbo |
| collection | DOAJ |
| description | Case summary A 2-year-old neutered female domestic shorthair cat presented with a history of hypodipsia, recurrent hypernatraemia, pelvic limb ataxia and tremor. The serum arginine vasopressin level was low for the serum osmolality. MRI of the brain revealed a failure of separation of the cerebrum, which manifested as absence of the rostral part of the corpus callosum, fornix and septum pellucidum, thus resulting in a single fused ventricle. The diagnosis was lobar holoprosencephaly with hypodipsic hypernatraemia. Relevance and novel information To our knowledge, this is the first description of the MRI characteristics of lobar holoprosencephaly in a cat. This report suggests that MRI examination should be considered for precise diagnosis of hypodipsic hypernatraemia in young cats. |
| first_indexed | 2024-12-11T12:18:40Z |
| format | Article |
| id | doaj.art-ea093b2a82da4221a8a520ec0f1bf425 |
| institution | Directory Open Access Journal |
| issn | 2055-1169 |
| language | English |
| last_indexed | 2024-12-11T12:18:40Z |
| publishDate | 2018-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Feline Medicine and Surgery Open Reports |
| spelling | doaj.art-ea093b2a82da4221a8a520ec0f1bf4252022-12-22T01:07:36ZengSAGE PublishingJournal of Feline Medicine and Surgery Open Reports2055-11692018-09-01410.1177/2055116918801602MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemiaGenya Shimbo0Michihito Tagawa1Masashi Yanagawa2Kazuro Miyahara3Current address: Veterinary Teaching Hospital, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, JapanVeterinary Medical Center, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, JapanDepartment of Veterinary Medicine, Division of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, JapanVeterinary Medical Center, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, JapanCase summary A 2-year-old neutered female domestic shorthair cat presented with a history of hypodipsia, recurrent hypernatraemia, pelvic limb ataxia and tremor. The serum arginine vasopressin level was low for the serum osmolality. MRI of the brain revealed a failure of separation of the cerebrum, which manifested as absence of the rostral part of the corpus callosum, fornix and septum pellucidum, thus resulting in a single fused ventricle. The diagnosis was lobar holoprosencephaly with hypodipsic hypernatraemia. Relevance and novel information To our knowledge, this is the first description of the MRI characteristics of lobar holoprosencephaly in a cat. This report suggests that MRI examination should be considered for precise diagnosis of hypodipsic hypernatraemia in young cats.https://doi.org/10.1177/2055116918801602 |
| spellingShingle | Genya Shimbo Michihito Tagawa Masashi Yanagawa Kazuro Miyahara MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia Journal of Feline Medicine and Surgery Open Reports |
| title | MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia |
| title_full | MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia |
| title_fullStr | MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia |
| title_full_unstemmed | MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia |
| title_short | MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia |
| title_sort | mri of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia |
| url | https://doi.org/10.1177/2055116918801602 |
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