Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development
Succinylation represents an emerging class of post-translational modifications (PTMs), characterized by the enzymatic or non-enzymatic transfer of a negatively charged four-carbon succinyl group to the ϵ-amino group of lysine residues, mediated by succinyl-coenzyme A. Recent studies have highlighted...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Sprog: | English |
Udgivet: |
Frontiers Media S.A.
2025-01-01
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Serier: | Frontiers in Immunology |
Fag: | |
Online adgang: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1531246/full |