Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development

Succinylation represents an emerging class of post-translational modifications (PTMs), characterized by the enzymatic or non-enzymatic transfer of a negatively charged four-carbon succinyl group to the ϵ-amino group of lysine residues, mediated by succinyl-coenzyme A. Recent studies have highlighted...

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Detalles Bibliográficos
Autores principales: Zhangmin Ke, Kaikai Shen, Li Wang, Hao Xu, Xia Pan, Zhenjue Qian, Yuting Wen, Tangfeng Lv, Xiuwei Zhang, Yong Song
Formato: Artículo
Lenguaje:English
Publicado: Frontiers Media S.A. 2025-01-01
Colección:Frontiers in Immunology
Materias:
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1531246/full