Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli-lipopolysaccharide, whereas it modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages

Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli-lipopolysaccharide, whereas it modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages

ABSTRACT Fasciola hepatica is known to suppress antigen-specific Th1 responses in concurrent bacterial infections while promoting the Th2/Treg regulatory responses. We have recently demonstrated that a single intraperitoneal injection with native F. hepatica glutathione S-transferase (nFhGST) mu-cla...

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Bibliographic Details
Main Authors: Bianca N. Valdes-Fernandez, Caleb Ruiz-Jimenez, Albersy Armina-Rodriguez, Loyda B. Mendez, Ana M. Espino
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
Fasciola hepatica
sepsis
glutathione S-transferase mu-class
cytokine storm
alternative activation of macrophages
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03475-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03475-23

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