Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli-lipopolysaccharide, whereas it modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages
ABSTRACT Fasciola hepatica is known to suppress antigen-specific Th1 responses in concurrent bacterial infections while promoting the Th2/Treg regulatory responses. We have recently demonstrated that a single intraperitoneal injection with native F. hepatica glutathione S-transferase (nFhGST) mu-cla...
Main Authors: | Bianca N. Valdes-Fernandez, Caleb Ruiz-Jimenez, Albersy Armina-Rodriguez, Loyda B. Mendez, Ana M. Espino |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2024-01-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.03475-23 |
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