Orchestration of Immune Cells Contributes to Fibrosis in IgG4-Related Disease

Orchestration of Immune Cells Contributes to Fibrosis in IgG4-Related Disease

This review summarizes recent progress in understanding the pathogenesis of IgG4-related disease (IgG4-RD), with a focus on fibrosis. Several studies reported that CD4<sup>+</sup> T cells with cytotoxic activity promoted by the secretion of granzyme and perforin, cytotoxic CD4<sup>...

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Bibliographic Details
Main Authors:	Naoki Kaneko, Masafumi Moriyama, Takashi Maehara, Hu Chen, Yuka Miyahara, Seiji Nakamura
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Immuno
Subjects:	cytotoxic CD4<sup>+</sup> T cells activated B cells macrophages fibrosis IgG4-related disease
Online Access:	https://www.mdpi.com/2673-5601/2/1/13

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