Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases

Purpose: Renal calculi are becoming more common among children. Although, extracorporeal shock wave lithotripsy (ESWL) is the first choice in this age group, minimal invasive surgeries, such as percutaneous nephrolithotomy (PCNL), are indicated for some patients. Recently, PCNL devices have become s...

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Main Authors: Mohammad Mehdi Hosseini, Dariush Irani, Ala'a Altofeyli, Ali Eslahi, Mitra Basiratnia, Abdolreza Haghpanah, Ali Adib, Faisal Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2021.613812/full
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author Mohammad Mehdi Hosseini
Dariush Irani
Ala'a Altofeyli
Ali Eslahi
Mitra Basiratnia
Abdolreza Haghpanah
Ali Adib
Faisal Ahmed
author_facet Mohammad Mehdi Hosseini
Dariush Irani
Ala'a Altofeyli
Ali Eslahi
Mitra Basiratnia
Abdolreza Haghpanah
Ali Adib
Faisal Ahmed
author_sort Mohammad Mehdi Hosseini
collection DOAJ
description Purpose: Renal calculi are becoming more common among children. Although, extracorporeal shock wave lithotripsy (ESWL) is the first choice in this age group, minimal invasive surgeries, such as percutaneous nephrolithotomy (PCNL), are indicated for some patients. Recently, PCNL devices have become smaller in size with acceptable efficacy and lower complications. We evaluated the outcomes and complications of mini-PCNL (MPCNL) surgery in our referral training centers.Materials and Methods: Between September 2012 and January 2020, a total of 112 children under the age of 18, who had shown failure of ESWL, and/or their parents refused to do it, underwent MPCNL (15 Fr). The patients' profiles were reviewed for data collection including preoperative and stone data, operation information, and postoperative complications.Results: Of 112 patients, 69 were boys, and 43 were girls. Their mean age was 8.6 years (14 months to 18 years). Mean stone size was 20 mm (14–34 mm). Seventy-four cases had renal pelvic stone, 22 had pelvis and lower pole, and 16 had staghorn. The mean operation time was 65 min (35–100 min), and mean radiation time was 0.6 min (0.2–1.4 min). Low-grade fever was detected in 14 patients (12.5%). Four patients needed blood transfusion and two had increased creatinine, which improved with conservative management. One patient developed urosepsis that resolved with antibiotic therapy. None of the patients had kidney perforation or other organ injury or death. Early stone-free rate (SFR) after operation was 90.2% (101 patients). Six patients had residual fragment <5 mm, which passed spontaneously in 2 weeks after operation (total SFR 95.3%). Three patients underwent second-look nephroscopy, and ureteroscopy was done for two patients due to migrated stone fragments to the distal ureter.Conclusion: MPCNL is recommended as a safe alternative option for treatment of the nephrolithiasis in children with good outcome and acceptable complications.
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spelling doaj.art-ea1244b5327443eb9f955709b74565e62022-12-21T18:58:06ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2021-06-01810.3389/fsurg.2021.613812613812Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 CasesMohammad Mehdi Hosseini0Dariush Irani1Ala'a Altofeyli2Ali Eslahi3Mitra Basiratnia4Abdolreza Haghpanah5Ali Adib6Faisal Ahmed7Shiraz Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Urology, Shaheed Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Urology, Shaheed Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IranShiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, IranShiraz Nephrology-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Urology, Shaheed Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IranStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Urology, Urology Research Center, Al-Thora General Hospital, Ibb University of Medical Since, Ibb, YemenPurpose: Renal calculi are becoming more common among children. Although, extracorporeal shock wave lithotripsy (ESWL) is the first choice in this age group, minimal invasive surgeries, such as percutaneous nephrolithotomy (PCNL), are indicated for some patients. Recently, PCNL devices have become smaller in size with acceptable efficacy and lower complications. We evaluated the outcomes and complications of mini-PCNL (MPCNL) surgery in our referral training centers.Materials and Methods: Between September 2012 and January 2020, a total of 112 children under the age of 18, who had shown failure of ESWL, and/or their parents refused to do it, underwent MPCNL (15 Fr). The patients' profiles were reviewed for data collection including preoperative and stone data, operation information, and postoperative complications.Results: Of 112 patients, 69 were boys, and 43 were girls. Their mean age was 8.6 years (14 months to 18 years). Mean stone size was 20 mm (14–34 mm). Seventy-four cases had renal pelvic stone, 22 had pelvis and lower pole, and 16 had staghorn. The mean operation time was 65 min (35–100 min), and mean radiation time was 0.6 min (0.2–1.4 min). Low-grade fever was detected in 14 patients (12.5%). Four patients needed blood transfusion and two had increased creatinine, which improved with conservative management. One patient developed urosepsis that resolved with antibiotic therapy. None of the patients had kidney perforation or other organ injury or death. Early stone-free rate (SFR) after operation was 90.2% (101 patients). Six patients had residual fragment <5 mm, which passed spontaneously in 2 weeks after operation (total SFR 95.3%). Three patients underwent second-look nephroscopy, and ureteroscopy was done for two patients due to migrated stone fragments to the distal ureter.Conclusion: MPCNL is recommended as a safe alternative option for treatment of the nephrolithiasis in children with good outcome and acceptable complications.https://www.frontiersin.org/articles/10.3389/fsurg.2021.613812/fullminimal invasivenephrolithiasisnephrolithotomypediatricsmini-percutaneous
spellingShingle Mohammad Mehdi Hosseini
Dariush Irani
Ala'a Altofeyli
Ali Eslahi
Mitra Basiratnia
Abdolreza Haghpanah
Ali Adib
Faisal Ahmed
Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases
Frontiers in Surgery
minimal invasive
nephrolithiasis
nephrolithotomy
pediatrics
mini-percutaneous
title Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases
title_full Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases
title_fullStr Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases
title_full_unstemmed Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases
title_short Outcome of Mini-Percutaneous Nephrolithotomy in Patients Under the Age of 18: An Experience With 112 Cases
title_sort outcome of mini percutaneous nephrolithotomy in patients under the age of 18 an experience with 112 cases
topic minimal invasive
nephrolithiasis
nephrolithotomy
pediatrics
mini-percutaneous
url https://www.frontiersin.org/articles/10.3389/fsurg.2021.613812/full
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