METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification

METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification

Background: Osteosarcoma (OS) is the most prevalent bone cancer among children and adolescents, with relatively high mortality rates. RNA N6-methyladenosine (m6A) is the most common human mRNA modification with diverse functions in a variety of biological processes. Previous studies indicated that m...

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Bibliographic Details
Main Authors: Xinying Zhou, Yang Yang, Yuejun Li, Guojun Liang, Dawei Kang, Bing Zhou, Qingchu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteosarcoma
m6A modification
METTL3
lncRNA DANCR
mRNA stability
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.784719/full

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