Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques

The conventional methods of cancer treatment and diagnosis, such as radiotherapy, chemotherapy, and computed tomography, have developed a great deal. However, the effectiveness of such methods is limited to the possible failure or collateral effects on the patients. In recent years, nanoscale materi...

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Main Authors: Simona Tarantino, Anna Paola Caricato, Rosaria Rinaldi, Caterina Capomolla, Valeria De Matteis
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/2/500
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author Simona Tarantino
Anna Paola Caricato
Rosaria Rinaldi
Caterina Capomolla
Valeria De Matteis
author_facet Simona Tarantino
Anna Paola Caricato
Rosaria Rinaldi
Caterina Capomolla
Valeria De Matteis
author_sort Simona Tarantino
collection DOAJ
description The conventional methods of cancer treatment and diagnosis, such as radiotherapy, chemotherapy, and computed tomography, have developed a great deal. However, the effectiveness of such methods is limited to the possible failure or collateral effects on the patients. In recent years, nanoscale materials have been studied in the field of medical physics to develop increasingly efficient methods to treat diseases. Gold nanoparticles (AuNPs), thanks to their unique physicochemical and optical properties, were introduced to medicine to promote highly effective treatments. Several studies have confirmed the advantages of AuNPs such as their biocompatibility and the possibility to tune their shapes and sizes or modify their surfaces using different chemical compounds. In this review, the main properties of AuNPs are analyzed, with particular focus on star-shaped AuNPs. In addition, the main methods of tumor treatment and diagnosis involving AuNPs are reviewed.
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spelling doaj.art-ea1971860fc149f1b7d792e5cacc20412023-11-16T22:40:47ZengMDPI AGPharmaceutics1999-49232023-02-0115250010.3390/pharmaceutics15020500Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical TechniquesSimona Tarantino0Anna Paola Caricato1Rosaria Rinaldi2Caterina Capomolla3Valeria De Matteis4Department of Mathematics and Physics “E. De Giorgi”, University of Salento, Via Monteroni, 73100 Lecce, ItalyDepartment of Mathematics and Physics “E. De Giorgi”, University of Salento, Via Monteroni, 73100 Lecce, ItalyDepartment of Mathematics and Physics “E. De Giorgi”, University of Salento, Via Monteroni, 73100 Lecce, Italy“Vito Fazzi” Hospital of Lecce, Oncological Center, Piazza Filippo Muratore 1, 73100 Lecce, ItalyDepartment of Mathematics and Physics “E. De Giorgi”, University of Salento, Via Monteroni, 73100 Lecce, ItalyThe conventional methods of cancer treatment and diagnosis, such as radiotherapy, chemotherapy, and computed tomography, have developed a great deal. However, the effectiveness of such methods is limited to the possible failure or collateral effects on the patients. In recent years, nanoscale materials have been studied in the field of medical physics to develop increasingly efficient methods to treat diseases. Gold nanoparticles (AuNPs), thanks to their unique physicochemical and optical properties, were introduced to medicine to promote highly effective treatments. Several studies have confirmed the advantages of AuNPs such as their biocompatibility and the possibility to tune their shapes and sizes or modify their surfaces using different chemical compounds. In this review, the main properties of AuNPs are analyzed, with particular focus on star-shaped AuNPs. In addition, the main methods of tumor treatment and diagnosis involving AuNPs are reviewed.https://www.mdpi.com/1999-4923/15/2/500cancerdiagnosticsmedical physicstherapynanomedicinegold nanoparticles
spellingShingle Simona Tarantino
Anna Paola Caricato
Rosaria Rinaldi
Caterina Capomolla
Valeria De Matteis
Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques
Pharmaceutics
cancer
diagnostics
medical physics
therapy
nanomedicine
gold nanoparticles
title Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques
title_full Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques
title_fullStr Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques
title_full_unstemmed Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques
title_short Cancer Treatment Using Different Shapes of Gold-Based Nanomaterials in Combination with Conventional Physical Techniques
title_sort cancer treatment using different shapes of gold based nanomaterials in combination with conventional physical techniques
topic cancer
diagnostics
medical physics
therapy
nanomedicine
gold nanoparticles
url https://www.mdpi.com/1999-4923/15/2/500
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