Detecting host responses to microbial stimulation using primary epithelial organoids

Detecting host responses to microbial stimulation using primary epithelial organoids

ABSTRACTThe intestinal epithelium is constantly exposed to microbes residing in the lumen. Traditionally, the response to microbial interactions has been studied in cell lines derived from cancerous tissues, e.g. Caco-2. It is, however, unclear how the responses in these cancer cell lines reflect th...

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Bibliographic Details
Main Authors: Jette Bornholdt, Christina V. Müller, Maria Juul Nielsen, Jesper Strickertsson, Daria Rago, Yun Chen, Grzegorz Maciag, Jonathan Skov, Anja Wellejus, Pawel J. Schweiger, Stine L. Hansen, Christa Broholm, Ismail Gögenur, Martti Maimets, Stine Sloth, Jakob Hendel, Adam Baker, Albin Sandelin, Kim B. Jensen
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Intestinal organoids
probiotics
microbiome
intestinal epithelium
bacterial–epithelial interactions
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2281012

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