Evaluation of a quantitative PCR-based method for chimerism analysis of Japanese donor/recipient pairs

Evaluation of a quantitative PCR-based method for chimerism analysis of Japanese donor/recipient pairs

Abstract Chimerism analysis is a surrogate indicator of graft rejection or relapse after allogeneic hematopoietic stem cell transplantation (HSCT). Although short tandem repeat PCR (STR-PCR) is the usual method, limited sensitivity and technical variability are matters of concern. Quantitative PCR-b...

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Bibliographic Details
Main Authors: Keiji Minakawa, Satoshi Ono, Mao Watanabe, Yuka Sato, Saki Suzuki, Shou Odawara, Kinuyo Kawabata, Koki Ueda, Kenneth E. Nollet, Hideki Sano, Takayuki Ikezoe, Atsushi Kikuta, Kazuhiko Ikeda
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25878-9

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https://doi.org/10.1038/s41598-022-25878-9

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