Recent Research Advances in Mitosis during Mammalian Gametogenesis
Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis. In the past few years, substantial research progress has be...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-06-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/8/6/567 |
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| author | Jia-Hao Wang Yan Li Shou-Long Deng Yi-Xun Liu Zheng-Xing Lian Kun Yu |
| author_facet | Jia-Hao Wang Yan Li Shou-Long Deng Yi-Xun Liu Zheng-Xing Lian Kun Yu |
| author_sort | Jia-Hao Wang |
| collection | DOAJ |
| description | Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis. In the past few years, substantial research progress has been made by showing that cyclins/cyclin-dependent kinase (CDK) have roles in the regulation of meiosis. In addition, more functional signaling molecules have been discovered in mitosis. Growing evidence has also indicated that miRNAs influence cell cycling. In this review, we focus on specific genes, cyclins/Cdk, signaling pathways/molecules, and miRNAs to discuss the latest achievements in understanding their roles in mitosis during gametogenesis. Further elucidation of mitosis during gametogenesis may facilitate delineating all processes of mammalian reproduction and the development of disease treatments. |
| first_indexed | 2024-03-12T08:15:21Z |
| format | Article |
| id | doaj.art-ea1f8e3a54344917ae41dfd4a7fe0bee |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-12T08:15:21Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-ea1f8e3a54344917ae41dfd4a7fe0bee2023-09-02T18:58:13ZengMDPI AGCells2073-44092019-06-018656710.3390/cells8060567cells8060567Recent Research Advances in Mitosis during Mammalian GametogenesisJia-Hao Wang0Yan Li1Shou-Long Deng2Yi-Xun Liu3Zheng-Xing Lian4Kun Yu5Beijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100193, ChinaBeijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100193, ChinaCAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, ChinaState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, ChinaBeijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100193, ChinaBeijing Key Laboratory for Animal Genetic Improvement, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, College of Animal Science and Technology, China Agricultural University, Beijing 100193, ChinaMitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis. In the past few years, substantial research progress has been made by showing that cyclins/cyclin-dependent kinase (CDK) have roles in the regulation of meiosis. In addition, more functional signaling molecules have been discovered in mitosis. Growing evidence has also indicated that miRNAs influence cell cycling. In this review, we focus on specific genes, cyclins/Cdk, signaling pathways/molecules, and miRNAs to discuss the latest achievements in understanding their roles in mitosis during gametogenesis. Further elucidation of mitosis during gametogenesis may facilitate delineating all processes of mammalian reproduction and the development of disease treatments.https://www.mdpi.com/2073-4409/8/6/567mitosismammalian gametescyclins/Cdk |
| spellingShingle | Jia-Hao Wang Yan Li Shou-Long Deng Yi-Xun Liu Zheng-Xing Lian Kun Yu Recent Research Advances in Mitosis during Mammalian Gametogenesis Cells mitosis mammalian gametes cyclins/Cdk |
| title | Recent Research Advances in Mitosis during Mammalian Gametogenesis |
| title_full | Recent Research Advances in Mitosis during Mammalian Gametogenesis |
| title_fullStr | Recent Research Advances in Mitosis during Mammalian Gametogenesis |
| title_full_unstemmed | Recent Research Advances in Mitosis during Mammalian Gametogenesis |
| title_short | Recent Research Advances in Mitosis during Mammalian Gametogenesis |
| title_sort | recent research advances in mitosis during mammalian gametogenesis |
| topic | mitosis mammalian gametes cyclins/Cdk |
| url | https://www.mdpi.com/2073-4409/8/6/567 |
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