Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction
Abstract A single-blind study to investigate the effects of noisy galvanic vestibular stimulation (nGVS) in straight walking and 2 Hz head yaw walking for healthy and bilateral vestibular hypofunction (BVH) participants in light and dark conditions. The optimal stimulation intensity for each partici...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-02-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-83206-z |
| _version_ | 1818424743019151360 |
|---|---|
| author | Po-Yin Chen Ying-Chun Jheng Chien-Chih Wang Shih-En Huang Ting-Hua Yang Po-Cheng Hsu Chia-Hua Kuo Yi-Ying Lin Wei-Yi Lai Chung-Lan Kao |
| author_facet | Po-Yin Chen Ying-Chun Jheng Chien-Chih Wang Shih-En Huang Ting-Hua Yang Po-Cheng Hsu Chia-Hua Kuo Yi-Ying Lin Wei-Yi Lai Chung-Lan Kao |
| author_sort | Po-Yin Chen |
| collection | DOAJ |
| description | Abstract A single-blind study to investigate the effects of noisy galvanic vestibular stimulation (nGVS) in straight walking and 2 Hz head yaw walking for healthy and bilateral vestibular hypofunction (BVH) participants in light and dark conditions. The optimal stimulation intensity for each participant was determined by calculating standing stability on a force plate while randomly applying six graded nGVS intensities (0–1000 µA). The chest–pelvic (C/P) ratio and lateral deviation of the center of mass (COM) were measured by motion capture during straight and 2 Hz head yaw walking in light and dark conditions. Participants were blinded to nGVS served randomly and imperceivably. Ten BVH patients and 16 healthy participants completed all trials. In the light condition, the COM lateral deviation significantly decreased only in straight walking (p = 0.037) with nGVS for the BVH. In the dark condition, both healthy (p = 0.026) and BVH (p = 0.017) exhibited decreased lateral deviation during nGVS. The C/P ratio decreased significantly in BVH for 2 Hz head yaw walking with nGVS (p = 0.005) in light conditions. This study demonstrated that nGVS effectively reduced walking deviations, especially in visual deprived condition for the BVH. Applying nGVS with different head rotation frequencies and light exposure levels may accelerate the rehabilitation process for patients with BVH. Clinical Trial Registration This clinical trial was prospectively registered at www.clinicaltrials.gov with the Unique identifier: NCT03554941. Date of registration: (13/06/2018). |
| first_indexed | 2024-12-14T14:02:53Z |
| format | Article |
| id | doaj.art-ea213d95e9874bef8ba183164a7b8f14 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-14T14:02:53Z |
| publishDate | 2021-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ea213d95e9874bef8ba183164a7b8f142022-12-21T22:58:41ZengNature PortfolioScientific Reports2045-23222021-02-0111111010.1038/s41598-021-83206-zEffect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunctionPo-Yin Chen0Ying-Chun Jheng1Chien-Chih Wang2Shih-En Huang3Ting-Hua Yang4Po-Cheng Hsu5Chia-Hua Kuo6Yi-Ying Lin7Wei-Yi Lai8Chung-Lan Kao9Department of Physical Therapy and Assistive Technology, National Yang-Ming Chiao-Tung UniversityDepartment of Physical Therapy and Assistive Technology, National Yang-Ming Chiao-Tung UniversitySchool of Medicine, National Yang-Ming Chiao-Tung UniversityDepartment of Physical Therapy and Assistive Technology, National Yang-Ming Chiao-Tung UniversityDepartment of Otolaryngology, College of Medicine, National Taiwan UniversityPhysical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu BranchDepartment of Sports Sciences, University of TaipeiSchool of Medicine, National Yang-Ming Chiao-Tung UniversitySchool of Medicine, National Yang-Ming Chiao-Tung UniversityDepartment of Physical Medicine and Rehabilitation, Taipei Veterans General HospitalAbstract A single-blind study to investigate the effects of noisy galvanic vestibular stimulation (nGVS) in straight walking and 2 Hz head yaw walking for healthy and bilateral vestibular hypofunction (BVH) participants in light and dark conditions. The optimal stimulation intensity for each participant was determined by calculating standing stability on a force plate while randomly applying six graded nGVS intensities (0–1000 µA). The chest–pelvic (C/P) ratio and lateral deviation of the center of mass (COM) were measured by motion capture during straight and 2 Hz head yaw walking in light and dark conditions. Participants were blinded to nGVS served randomly and imperceivably. Ten BVH patients and 16 healthy participants completed all trials. In the light condition, the COM lateral deviation significantly decreased only in straight walking (p = 0.037) with nGVS for the BVH. In the dark condition, both healthy (p = 0.026) and BVH (p = 0.017) exhibited decreased lateral deviation during nGVS. The C/P ratio decreased significantly in BVH for 2 Hz head yaw walking with nGVS (p = 0.005) in light conditions. This study demonstrated that nGVS effectively reduced walking deviations, especially in visual deprived condition for the BVH. Applying nGVS with different head rotation frequencies and light exposure levels may accelerate the rehabilitation process for patients with BVH. Clinical Trial Registration This clinical trial was prospectively registered at www.clinicaltrials.gov with the Unique identifier: NCT03554941. Date of registration: (13/06/2018).https://doi.org/10.1038/s41598-021-83206-z |
| spellingShingle | Po-Yin Chen Ying-Chun Jheng Chien-Chih Wang Shih-En Huang Ting-Hua Yang Po-Cheng Hsu Chia-Hua Kuo Yi-Ying Lin Wei-Yi Lai Chung-Lan Kao Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction Scientific Reports |
| title | Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction |
| title_full | Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction |
| title_fullStr | Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction |
| title_full_unstemmed | Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction |
| title_short | Effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction |
| title_sort | effect of noisy galvanic vestibular stimulation on dynamic posture sway under visual deprivation in patients with bilateral vestibular hypofunction |
| url | https://doi.org/10.1038/s41598-021-83206-z |
| work_keys_str_mv | AT poyinchen effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT yingchunjheng effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT chienchihwang effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT shihenhuang effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT tinghuayang effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT pochenghsu effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT chiahuakuo effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT yiyinglin effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT weiyilai effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction AT chunglankao effectofnoisygalvanicvestibularstimulationondynamicpostureswayundervisualdeprivationinpatientswithbilateralvestibularhypofunction |