Brain Epitranscriptomic Analysis Revealed Altered A-to-I RNA Editing in Septic Patients

Brain Epitranscriptomic Analysis Revealed Altered A-to-I RNA Editing in Septic Patients

Recent studies suggest that RNA editing is associated with impaired brain function and neurological and psychiatric disorders. However, the role of A-to-I RNA editing during sepsis-associated encephalopathy (SAE) remains unclear. In this study, we analyzed adenosine-to-inosine (A-to-I) RNA editing i...

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Bibliographic Details
Main Authors: Jing-Qian Zhang, Jia-Qi Pan, Zhi-Yuan Wei, Chun-Yan Ren, Fu-Xia Ru, Shou-Yue Xia, Yu-Shan He, Kaisheng Lin, Jian-Huan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
RNA editing
sepsis-associated encephalopathy
human brain
cis-regulatory analysis
epitranscriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.887001/full

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