Prospects of fermented milk products in children with primary hypolactasia of the adult type
Lactose (β-galactosyl-1,4 glucose) is milk sugar, the main disaccharide of human and other mammalian breast milk. Lactase is intestinal disaccharidase that catalyzes the lactose hydrolysis. The lactase gene LCT controls biological function of the enzyme. The age-related genetically determined featur...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2020-07-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/1165 |
| _version_ | 1797875136868646912 |
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| author | N. M. Bogdanova A. I. Khavkin O. L. Kolobova |
| author_facet | N. M. Bogdanova A. I. Khavkin O. L. Kolobova |
| author_sort | N. M. Bogdanova |
| collection | DOAJ |
| description | Lactose (β-galactosyl-1,4 glucose) is milk sugar, the main disaccharide of human and other mammalian breast milk. Lactase is intestinal disaccharidase that catalyzes the lactose hydrolysis. The lactase gene LCT controls biological function of the enzyme. The age-related genetically determined feature of disaccharide expression, epigenetic factors, and natural selection with persistent tolerance to milk sugar throughout lifetime has divided the human population according to the LCT gene into two phenotypes: lactase persistent and lactase non-persistent. There is conflicting evidence that the latter phenotype is associated with low calcium absorption and the development of osteoporosis. The regular use of fermented probiotic dairy products by individuals with the lactase non-persistence phenotype ensures the accumulation of peak bone mineralization and prevents osteoporosis. |
| first_indexed | 2024-04-10T01:42:56Z |
| format | Article |
| id | doaj.art-ea225b98bf884307bc7fc2e054079be5 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:42:56Z |
| publishDate | 2020-07-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-ea225b98bf884307bc7fc2e054079be52023-03-13T09:12:49ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282020-07-0165316016810.21508/1027-4065-2020-65-3-160-168901Prospects of fermented milk products in children with primary hypolactasia of the adult typeN. M. Bogdanova0A. I. Khavkin1O. L. Kolobova2ФГБОУ ВО Санкт-Петербургский государственный педиатрический медицинский университет Минздрава РоссииОСП «Научно-исследовательский клинический институт педиатрии им. академика Ю.Е. Вельтищева» ФГБАУ ВО РНИМУ им. Н.И. Пирогова Минздрава РоссииФГБОУ ВО Санкт-Петербургский государственный педиатрический медицинский университет Минздрава РоссииLactose (β-galactosyl-1,4 glucose) is milk sugar, the main disaccharide of human and other mammalian breast milk. Lactase is intestinal disaccharidase that catalyzes the lactose hydrolysis. The lactase gene LCT controls biological function of the enzyme. The age-related genetically determined feature of disaccharide expression, epigenetic factors, and natural selection with persistent tolerance to milk sugar throughout lifetime has divided the human population according to the LCT gene into two phenotypes: lactase persistent and lactase non-persistent. There is conflicting evidence that the latter phenotype is associated with low calcium absorption and the development of osteoporosis. The regular use of fermented probiotic dairy products by individuals with the lactase non-persistence phenotype ensures the accumulation of peak bone mineralization and prevents osteoporosis.https://www.ped-perinatology.ru/jour/article/view/1165детилактозалактазанепереносимость лактозылактазная недостаточностьпервичная гиполактазия взрослого типаминеральная плотность костной тканипробиотикиферментированные молочные продуктыдиетотерапия |
| spellingShingle | N. M. Bogdanova A. I. Khavkin O. L. Kolobova Prospects of fermented milk products in children with primary hypolactasia of the adult type Rossijskij Vestnik Perinatologii i Pediatrii дети лактоза лактаза непереносимость лактозы лактазная недостаточность первичная гиполактазия взрослого типа минеральная плотность костной ткани пробиотики ферментированные молочные продукты диетотерапия |
| title | Prospects of fermented milk products in children with primary hypolactasia of the adult type |
| title_full | Prospects of fermented milk products in children with primary hypolactasia of the adult type |
| title_fullStr | Prospects of fermented milk products in children with primary hypolactasia of the adult type |
| title_full_unstemmed | Prospects of fermented milk products in children with primary hypolactasia of the adult type |
| title_short | Prospects of fermented milk products in children with primary hypolactasia of the adult type |
| title_sort | prospects of fermented milk products in children with primary hypolactasia of the adult type |
| topic | дети лактоза лактаза непереносимость лактозы лактазная недостаточность первичная гиполактазия взрослого типа минеральная плотность костной ткани пробиотики ферментированные молочные продукты диетотерапия |
| url | https://www.ped-perinatology.ru/jour/article/view/1165 |
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