NF-κB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury

NF-κB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury

Spinal cord injury (SCI) leads to significant functional impairments below the level of the injury, and astrocytes play a crucial role in the pathophysiology of SCI. Astrocytes undergo changes and form a glial scar after SCI, which has traditionally been viewed as a barrier to axonal regeneration an...

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Bibliographic Details
Main Authors: Tatyana Ageeva, Albert Rizvanov, Yana Mukhamedshina
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
astrocyte
glial scar
JAK/STAT
NF-κB
spinal cord injury
Online Access:https://www.mdpi.com/2073-4409/13/7/581

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