Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease

It is thought that inhaled dusts such as asbestos and man-made mineral fibers in the lung repeatedly induce persistent inflammation and finally lead to pulmonary fibrosis and respiratory cancer. There have been many studies about whether a var...

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Main Authors: Hiroto Izumi, Yasuo Morimoto
Format: Article
Language:English
Published: Hosokawa Powder Technology Foundation 2014-02-01
Series:KONA Powder and Particle Journal
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/kona/31/0/31_2014019/_html/-char/en
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author Hiroto Izumi
Yasuo Morimoto
author_facet Hiroto Izumi
Yasuo Morimoto
author_sort Hiroto Izumi
collection DOAJ
description It is thought that inhaled dusts such as asbestos and man-made mineral fibers in the lung repeatedly induce persistent inflammation and finally lead to pulmonary fibrosis and respiratory cancer. There have been many studies about whether a variety of factors, such as oxidative stress including free radicals, chemokines, inflammatory cytokines, and fibrosis-related cytokines are related to pulmonary fibrosis, lung cancer and malignant mesothelioma. In this paper, we introduce the relationship between these factors and these diseases. It is important to determine what physicochemical properties of fibrous materials such as asbestos are related to asbestos-related diseases. We show the relationship between the physicochemical properties of not only asbestos but also other fibrous materials and inflammation, fibrosis and biopersistence in the lung.
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spelling doaj.art-ea26f90fcb144192af7ae5a03cf456b32022-12-21T22:43:04ZengHosokawa Powder Technology FoundationKONA Powder and Particle Journal0288-45342187-55372014-02-0131012613410.14356/kona.2014019konaPhysicochemical Properties and Factors that Induce Asbestos-Related Respiratory DiseaseHiroto Izumi0Yasuo Morimoto1Institute of Industrial Ecological Sciences, University of Occupational and Environmental HealthInstitute of Industrial Ecological Sciences, University of Occupational and Environmental HealthIt is thought that inhaled dusts such as asbestos and man-made mineral fibers in the lung repeatedly induce persistent inflammation and finally lead to pulmonary fibrosis and respiratory cancer. There have been many studies about whether a variety of factors, such as oxidative stress including free radicals, chemokines, inflammatory cytokines, and fibrosis-related cytokines are related to pulmonary fibrosis, lung cancer and malignant mesothelioma. In this paper, we introduce the relationship between these factors and these diseases. It is important to determine what physicochemical properties of fibrous materials such as asbestos are related to asbestos-related diseases. We show the relationship between the physicochemical properties of not only asbestos but also other fibrous materials and inflammation, fibrosis and biopersistence in the lung.https://www.jstage.jst.go.jp/article/kona/31/0/31_2014019/_html/-char/enasbestoslung cancermalignant mesotheliomacumulative exposure
spellingShingle Hiroto Izumi
Yasuo Morimoto
Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
KONA Powder and Particle Journal
asbestos
lung cancer
malignant mesothelioma
cumulative exposure
title Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
title_full Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
title_fullStr Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
title_full_unstemmed Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
title_short Physicochemical Properties and Factors that Induce Asbestos-Related Respiratory Disease
title_sort physicochemical properties and factors that induce asbestos related respiratory disease
topic asbestos
lung cancer
malignant mesothelioma
cumulative exposure
url https://www.jstage.jst.go.jp/article/kona/31/0/31_2014019/_html/-char/en
work_keys_str_mv AT hirotoizumi physicochemicalpropertiesandfactorsthatinduceasbestosrelatedrespiratorydisease
AT yasuomorimoto physicochemicalpropertiesandfactorsthatinduceasbestosrelatedrespiratorydisease