Fucoxantin: A Treasure from the Sea

The World Health Organization (WHO) estimates that 2.3 billion people will be overweight and 700 million obese in 2015. The reasons for this disastrous trend are attributed to the global tendency toward the reduced magnitude of exercise and physical activity and the increased dietary intake of fats,...

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Main Authors: Graziano Riccioni, Cristiana Ficoneri, Massimo de Girolamo, Maria Alessandra Gammone, Nicolantonio D’Orazio, Eugenio Gemello
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/10/3/604/
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author Graziano Riccioni
Cristiana Ficoneri
Massimo de Girolamo
Maria Alessandra Gammone
Nicolantonio D’Orazio
Eugenio Gemello
author_facet Graziano Riccioni
Cristiana Ficoneri
Massimo de Girolamo
Maria Alessandra Gammone
Nicolantonio D’Orazio
Eugenio Gemello
author_sort Graziano Riccioni
collection DOAJ
description The World Health Organization (WHO) estimates that 2.3 billion people will be overweight and 700 million obese in 2015. The reasons for this disastrous trend are attributed to the global tendency toward the reduced magnitude of exercise and physical activity and the increased dietary intake of fats, sugars and calories with reduced amount of vitamins and minerals. To prevent life-style-related diseases, like Metabolic Syndrome (MS), researchers’ attention is increasingly focusing on some of the so called “functional foods” which may be useful for their prevention and treatment. One of these functional ingredients is fucoxanthin (FX), a characteristic carotenoid present in edible brown seaweeds, such as Undaria pinnatifida (Wakame), Hijikia fusiformis (Hijiki), Laminaria japonica (Ma-Kombu) and Sargassum fulvellum. The increasing popularity of this molecule is certainly due to its anti-obesity effect, primarily detected by murine studies. These works revealed FX mediated induction of uncoupling protein-1 (UCP-1) in abdominal white adipose tissue (WAT) mitochondria, leading to the oxidation of fatty acids and heat production in WAT. Beyond this important role, in recent studies FX has shown a great antioxidant activity, anti-cancer, anti-diabetic and anti-photoaging properties. The aim of this review is to highlight the main effects of FX on human health.
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spelling doaj.art-ea270f614e774bfcb2e32f31c181d16d2022-12-22T03:58:44ZengMDPI AGMarine Drugs1660-33972012-03-0110360461610.3390/md10030604Fucoxantin: A Treasure from the SeaGraziano RiccioniCristiana FiconeriMassimo de GirolamoMaria Alessandra GammoneNicolantonio D’OrazioEugenio GemelloThe World Health Organization (WHO) estimates that 2.3 billion people will be overweight and 700 million obese in 2015. The reasons for this disastrous trend are attributed to the global tendency toward the reduced magnitude of exercise and physical activity and the increased dietary intake of fats, sugars and calories with reduced amount of vitamins and minerals. To prevent life-style-related diseases, like Metabolic Syndrome (MS), researchers’ attention is increasingly focusing on some of the so called “functional foods” which may be useful for their prevention and treatment. One of these functional ingredients is fucoxanthin (FX), a characteristic carotenoid present in edible brown seaweeds, such as Undaria pinnatifida (Wakame), Hijikia fusiformis (Hijiki), Laminaria japonica (Ma-Kombu) and Sargassum fulvellum. The increasing popularity of this molecule is certainly due to its anti-obesity effect, primarily detected by murine studies. These works revealed FX mediated induction of uncoupling protein-1 (UCP-1) in abdominal white adipose tissue (WAT) mitochondria, leading to the oxidation of fatty acids and heat production in WAT. Beyond this important role, in recent studies FX has shown a great antioxidant activity, anti-cancer, anti-diabetic and anti-photoaging properties. The aim of this review is to highlight the main effects of FX on human health.http://www.mdpi.com/1660-3397/10/3/604/obesityfucoxanthinbrown seaweedsantioxidantsnutritionfat
spellingShingle Graziano Riccioni
Cristiana Ficoneri
Massimo de Girolamo
Maria Alessandra Gammone
Nicolantonio D’Orazio
Eugenio Gemello
Fucoxantin: A Treasure from the Sea
Marine Drugs
obesity
fucoxanthin
brown seaweeds
antioxidants
nutrition
fat
title Fucoxantin: A Treasure from the Sea
title_full Fucoxantin: A Treasure from the Sea
title_fullStr Fucoxantin: A Treasure from the Sea
title_full_unstemmed Fucoxantin: A Treasure from the Sea
title_short Fucoxantin: A Treasure from the Sea
title_sort fucoxantin a treasure from the sea
topic obesity
fucoxanthin
brown seaweeds
antioxidants
nutrition
fat
url http://www.mdpi.com/1660-3397/10/3/604/
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