Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression

Han Zhang,1– 3 Yefan Zhang,1– 3 Sen Sheng,1,2 Yang Xing,4 Zhongchen Mou,5 Yanqiu Zhang,1– 3 Zhixue Shi,1– 3 Zhenjie Yu,1,2 Qianqian Gao,1– 3 Weiqin Cai,1– 3 Qi Jing1– 3 1School of Management, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2“Health Shandong” Collaborative...

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Main Authors: Zhang H, Zhang Y, Sheng S, Xing Y, Mou Z, Shi Z, Yu Z, Gao Q, Cai W, Jing Q
Format: Article
Language:English
Published: Dove Medical Press 2023-03-01
Series:Psychology Research and Behavior Management
Subjects:
Online Access:https://www.dovepress.com/relationship-between-physical-exercise-and-cognitive-impairment-among--peer-reviewed-fulltext-article-PRBM
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author Zhang H
Zhang Y
Sheng S
Xing Y
Mou Z
Zhang Y
Shi Z
Yu Z
Gao Q
Cai W
Jing Q
author_facet Zhang H
Zhang Y
Sheng S
Xing Y
Mou Z
Zhang Y
Shi Z
Yu Z
Gao Q
Cai W
Jing Q
author_sort Zhang H
collection DOAJ
description Han Zhang,1– 3 Yefan Zhang,1– 3 Sen Sheng,1,2 Yang Xing,4 Zhongchen Mou,5 Yanqiu Zhang,1– 3 Zhixue Shi,1– 3 Zhenjie Yu,1,2 Qianqian Gao,1– 3 Weiqin Cai,1– 3 Qi Jing1– 3 1School of Management, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2“Health Shandong” Collaborative Innovation Center for Severe Social Risk Prediction and Governance, Weifang, People’s Republic of China; 3China Academy of Rehabilitation and Health, Weifang Medical University, Weifang, People’s Republic of China; 4Weifang People’s Hospital, Weifang, People’s Republic of China; 5School of Psychology, Weifang Medical University, Weifang, People’s Republic of ChinaCorrespondence: Weiqin Cai; Qi Jing, School of Management, Weifang Medical University, No. 7166 Baotongxi Street, Weifang, 261053, People’s Republic of China, Tel +8618106369128, Email caiwq@wfmc.edu.cn; jingq@wfmc.edu.cnObjective: Although physical exercise has been shown to boost physical, psychological, and psychiatric conditions in older adults, there is a relative lack of research on the mechanisms involved in this process for older adults with type 2 diabetes mellitus (T2DM). We thus evaluated whether sleep quality and depression mediated the relationship between physical exercise and cognitive impairment in older adults with T2DM by focusing on the exercise–physiology–psychology and psychiatry connection.Methods: Self-reported data were collected from 2646 older adults with T2DM in Weifang, Shandong, China. Regression and bootstrap analyses were conducted to explore the chain mediator model including physical exercise, cognitive impairment, sleep quality, and depression.Results: Engaging in physical exercise (coefficient = − 0.6858, p < 0.001), high levels of sleep quality (coefficient = − 0.3397, p = 0.015), and low levels of depression (coefficient = 0.3866, p < 0.001) were significantly associated with a low level of cognitive impairment. Sleep quality and depression mediated the chain effect between physical exercise and cognitive impairment (total effect = − 1.0732, 95% CI [− 1.3652, − 0.7862]; direct effect = − 0.6858, 95% CI [− 0.9702, − 0.3974]; indirect effect = − 0.3875, 95% CI [− 0.5369, − 0.2521]).Conclusion: Physical exercise may improve sleep quality in older adults with T2DM, alleviating depression and delaying the development of cognitive impairment. Physical exercise can enhance patients’ ability to resist depression and cognitive impairment, and creating comfortable sleep environments can also reinforce the effects of this process. These findings have important implications for promoting healthy aging in older adults with T2DM.Keywords: physical exercise, cognitive impairment, older adults, depression, sleep quality, type 2 diabetes
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spelling doaj.art-ea27b57e2ea14743853ddc4a1e6667742023-03-19T18:35:52ZengDove Medical PressPsychology Research and Behavior Management1179-15782023-03-01Volume 1681782882366Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and DepressionZhang HZhang YSheng SXing YMou ZZhang YShi ZYu ZGao QCai WJing QHan Zhang,1– 3 Yefan Zhang,1– 3 Sen Sheng,1,2 Yang Xing,4 Zhongchen Mou,5 Yanqiu Zhang,1– 3 Zhixue Shi,1– 3 Zhenjie Yu,1,2 Qianqian Gao,1– 3 Weiqin Cai,1– 3 Qi Jing1– 3 1School of Management, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2“Health Shandong” Collaborative Innovation Center for Severe Social Risk Prediction and Governance, Weifang, People’s Republic of China; 3China Academy of Rehabilitation and Health, Weifang Medical University, Weifang, People’s Republic of China; 4Weifang People’s Hospital, Weifang, People’s Republic of China; 5School of Psychology, Weifang Medical University, Weifang, People’s Republic of ChinaCorrespondence: Weiqin Cai; Qi Jing, School of Management, Weifang Medical University, No. 7166 Baotongxi Street, Weifang, 261053, People’s Republic of China, Tel +8618106369128, Email caiwq@wfmc.edu.cn; jingq@wfmc.edu.cnObjective: Although physical exercise has been shown to boost physical, psychological, and psychiatric conditions in older adults, there is a relative lack of research on the mechanisms involved in this process for older adults with type 2 diabetes mellitus (T2DM). We thus evaluated whether sleep quality and depression mediated the relationship between physical exercise and cognitive impairment in older adults with T2DM by focusing on the exercise–physiology–psychology and psychiatry connection.Methods: Self-reported data were collected from 2646 older adults with T2DM in Weifang, Shandong, China. Regression and bootstrap analyses were conducted to explore the chain mediator model including physical exercise, cognitive impairment, sleep quality, and depression.Results: Engaging in physical exercise (coefficient = − 0.6858, p < 0.001), high levels of sleep quality (coefficient = − 0.3397, p = 0.015), and low levels of depression (coefficient = 0.3866, p < 0.001) were significantly associated with a low level of cognitive impairment. Sleep quality and depression mediated the chain effect between physical exercise and cognitive impairment (total effect = − 1.0732, 95% CI [− 1.3652, − 0.7862]; direct effect = − 0.6858, 95% CI [− 0.9702, − 0.3974]; indirect effect = − 0.3875, 95% CI [− 0.5369, − 0.2521]).Conclusion: Physical exercise may improve sleep quality in older adults with T2DM, alleviating depression and delaying the development of cognitive impairment. Physical exercise can enhance patients’ ability to resist depression and cognitive impairment, and creating comfortable sleep environments can also reinforce the effects of this process. These findings have important implications for promoting healthy aging in older adults with T2DM.Keywords: physical exercise, cognitive impairment, older adults, depression, sleep quality, type 2 diabeteshttps://www.dovepress.com/relationship-between-physical-exercise-and-cognitive-impairment-among--peer-reviewed-fulltext-article-PRBMphysical exercisecognitive impairmentolder adultsdepressionsleep qualitytype 2 diabetes.
spellingShingle Zhang H
Zhang Y
Sheng S
Xing Y
Mou Z
Zhang Y
Shi Z
Yu Z
Gao Q
Cai W
Jing Q
Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression
Psychology Research and Behavior Management
physical exercise
cognitive impairment
older adults
depression
sleep quality
type 2 diabetes.
title Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression
title_full Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression
title_fullStr Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression
title_full_unstemmed Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression
title_short Relationship Between Physical Exercise and Cognitive Impairment Among Older Adults with Type 2 Diabetes: Chain Mediating Roles of Sleep Quality and Depression
title_sort relationship between physical exercise and cognitive impairment among older adults with type 2 diabetes chain mediating roles of sleep quality and depression
topic physical exercise
cognitive impairment
older adults
depression
sleep quality
type 2 diabetes.
url https://www.dovepress.com/relationship-between-physical-exercise-and-cognitive-impairment-among--peer-reviewed-fulltext-article-PRBM
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