Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis
Abstract Background Cardiovascular disease continues to be a leading cause of mortality worldwide, highlighting the need to explore innovative approaches to improve cardiovascular health outcomes. Time-restricted fasting (TRF) is a dietary intervention that involves limiting the time window for food...
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| Format: | Article |
| Language: | English |
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BMC
2024-04-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-024-03863-6 |
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| author | Zhengqi Qiu Emma Yun Zhi Huang Yufei Li Ying Xiao Yancheng Fu Jun Du Juntao Kan |
| author_facet | Zhengqi Qiu Emma Yun Zhi Huang Yufei Li Ying Xiao Yancheng Fu Jun Du Juntao Kan |
| author_sort | Zhengqi Qiu |
| collection | DOAJ |
| description | Abstract Background Cardiovascular disease continues to be a leading cause of mortality worldwide, highlighting the need to explore innovative approaches to improve cardiovascular health outcomes. Time-restricted fasting (TRF) is a dietary intervention that involves limiting the time window for food consumption. It has gained attention for its potential benefits on metabolic health and weight management. This study aims to investigate the impact of TRF on key risk factors, including body weight, glucose metabolism, blood pressure, and lipid profile. Methods We conducted a systematic search in five databases (Scopus, Embase, PubMed, Cochrane, and Web of Science) for relevant studies up to January 2023. After applying inclusion criteria, 12 studies were eligible for analysis. Quality assessment was conducted using the ROB-2.0 tool and ROBINS-I. Risk of bias was mapped using Revman 5.3, and data analysis included Hartung-Knapp adjustment using R 4.2.2. Results The group that underwent the TRF intervention exhibited a significant decrease in body weight (SMD: -0.22; 95%CI: -0.41, -0.04; P < 0.05) and fat mass (SMD: -0.19; 95%CI: -0.36, -0.02; P < 0.05), while maintaining lean mass (SMD: -0.09; 95%CI: -0.08, 0.26; P > 0.05). Conclusion TRF has shown potential as a treatment strategy for reducing total body weight by targeting adipose tissue, with potential improvements in cardiometabolic function. |
| first_indexed | 2024-04-24T07:20:14Z |
| format | Article |
| id | doaj.art-ea29a7d609d64694a887f76fbe34795e |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-04-24T07:20:14Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-ea29a7d609d64694a887f76fbe34795e2024-04-21T11:08:01ZengBMCBMC Cardiovascular Disorders1471-22612024-04-0124111110.1186/s12872-024-03863-6Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysisZhengqi Qiu0Emma Yun Zhi Huang1Yufei Li2Ying Xiao3Yancheng Fu4Jun Du5Juntao Kan6Faculty of Medicine, Macau University of Science and TechnologyNutrilite Health InstituteFaculty of Medicine, Macau University of Science and TechnologyFaculty of Medicine, Macau University of Science and TechnologyDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Health Science Center, Shenzhen UniversityNutrilite Health InstituteNutrilite Health InstituteAbstract Background Cardiovascular disease continues to be a leading cause of mortality worldwide, highlighting the need to explore innovative approaches to improve cardiovascular health outcomes. Time-restricted fasting (TRF) is a dietary intervention that involves limiting the time window for food consumption. It has gained attention for its potential benefits on metabolic health and weight management. This study aims to investigate the impact of TRF on key risk factors, including body weight, glucose metabolism, blood pressure, and lipid profile. Methods We conducted a systematic search in five databases (Scopus, Embase, PubMed, Cochrane, and Web of Science) for relevant studies up to January 2023. After applying inclusion criteria, 12 studies were eligible for analysis. Quality assessment was conducted using the ROB-2.0 tool and ROBINS-I. Risk of bias was mapped using Revman 5.3, and data analysis included Hartung-Knapp adjustment using R 4.2.2. Results The group that underwent the TRF intervention exhibited a significant decrease in body weight (SMD: -0.22; 95%CI: -0.41, -0.04; P < 0.05) and fat mass (SMD: -0.19; 95%CI: -0.36, -0.02; P < 0.05), while maintaining lean mass (SMD: -0.09; 95%CI: -0.08, 0.26; P > 0.05). Conclusion TRF has shown potential as a treatment strategy for reducing total body weight by targeting adipose tissue, with potential improvements in cardiometabolic function.https://doi.org/10.1186/s12872-024-03863-6Cardiovascular diseaseTime-restricted fastingRhythmMeta-analysisWeight loss |
| spellingShingle | Zhengqi Qiu Emma Yun Zhi Huang Yufei Li Ying Xiao Yancheng Fu Jun Du Juntao Kan Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis BMC Cardiovascular Disorders Cardiovascular disease Time-restricted fasting Rhythm Meta-analysis Weight loss |
| title | Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis |
| title_full | Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis |
| title_fullStr | Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis |
| title_full_unstemmed | Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis |
| title_short | Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis |
| title_sort | beneficial effects of time restricted fasting on cardiovascular disease risk factors a meta analysis |
| topic | Cardiovascular disease Time-restricted fasting Rhythm Meta-analysis Weight loss |
| url | https://doi.org/10.1186/s12872-024-03863-6 |
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