A Method for Assessing the Robustness of Protein Structures by Randomizing Packing Interactions
Many single-domain proteins are not only stable and water-soluble, but they also populate few to no intermediates during folding. This reduces interactions between partially folded proteins, misfolding, and aggregation, and makes the proteins tractable in biotechnological applications. Natural prote...
Main Authors: | Shilpa Yadahalli, Lakshmi P. Jayanthi, Shachi Gosavi |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-06-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.849272/full |
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