GSK-J1-loaded, hyaluronic acid-decorated metal-organic frameworks for the treatment of ovarian cancer

GSK-J1-loaded, hyaluronic acid-decorated metal-organic frameworks for the treatment of ovarian cancer

Despite intensive research, ovarian cancer has the highest mortality rates among gynecological malignancies, partly because of its rapid acquisition of chemoresistance to platinum therapy. Hence, strategies are needed to effectively treat carboplatin-resistant ovarian cancer. In this study, we desig...

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Bibliographic Details
Main Authors: Bing Yang, Wenxu Liu, Meiying Li, Jingxin Mo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
ovarian cancer
hyaluronic acid
MOF
HER2
epigenetic modification
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1023719/full

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