Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images
Although the blood flow velocity in a left ventricle (LV) has been considered to be sufficiently fast to prevent thrombus formation, internal wall structures, such as trabeculae carneae (TC) and papillary muscle, recently received attention as possible causes of reduced near-wall blood flow. As a fu...
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Format: | Article |
Language: | English |
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The Japan Society of Mechanical Engineers
2018-04-01
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Series: | Journal of Biomechanical Science and Engineering |
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Online Access: | https://www.jstage.jst.go.jp/article/jbse/13/2/13_17-00597/_pdf/-char/en |
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author | Tomomi YAMADA Toshiyuki HAYASE Suguru MIYAUCHI Kenichi FUNAMOTO |
author_facet | Tomomi YAMADA Toshiyuki HAYASE Suguru MIYAUCHI Kenichi FUNAMOTO |
author_sort | Tomomi YAMADA |
collection | DOAJ |
description | Although the blood flow velocity in a left ventricle (LV) has been considered to be sufficiently fast to prevent thrombus formation, internal wall structures, such as trabeculae carneae (TC) and papillary muscle, recently received attention as possible causes of reduced near-wall blood flow. As a fundamental consideration of this problem, this study established a method for constructing an unsteady LV model from magnetic resonance (MR) images and investigated the effect of a few simplified TC structures on the blood flow in the model. The LV model at arbitrary time steps was constructed by deforming a computational mesh generated from MR images at a reference time step. The validity of the proposed construction scheme was confirmed by comparison with the configuration of an LV model extracted from MR images. Numerical analysis was performed for the unsteady blood flow in LV models with and without two simplified TC structures. The flow field in the model with the internal structure differed from that in the model without the internal structure near the wall, and flow separation caused by the internal structure decreased wall shear stress on the rear of the internal structure. The computational results provide fundamental information for the complex interaction between the internal structures and the blood flow in an LV. |
first_indexed | 2024-12-11T17:42:24Z |
format | Article |
id | doaj.art-ea321d7e4b61475989c8c65e84b5928a |
institution | Directory Open Access Journal |
issn | 1880-9863 |
language | English |
last_indexed | 2024-12-11T17:42:24Z |
publishDate | 2018-04-01 |
publisher | The Japan Society of Mechanical Engineers |
record_format | Article |
series | Journal of Biomechanical Science and Engineering |
spelling | doaj.art-ea321d7e4b61475989c8c65e84b5928a2022-12-22T00:56:30ZengThe Japan Society of Mechanical EngineersJournal of Biomechanical Science and Engineering1880-98632018-04-0113217-0059717-0059710.1299/jbse.17-00597jbseNumerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance imagesTomomi YAMADA0Toshiyuki HAYASE1Suguru MIYAUCHI2Kenichi FUNAMOTO3Graduate School of Biomedical Engineering, Tohoku UniversityInstitute of Fluid Science, Tohoku UniversityInstitute of Fluid Science, Tohoku UniversityFrontier Research Institute for Interdisciplinary Sciences, Tohoku UniversityAlthough the blood flow velocity in a left ventricle (LV) has been considered to be sufficiently fast to prevent thrombus formation, internal wall structures, such as trabeculae carneae (TC) and papillary muscle, recently received attention as possible causes of reduced near-wall blood flow. As a fundamental consideration of this problem, this study established a method for constructing an unsteady LV model from magnetic resonance (MR) images and investigated the effect of a few simplified TC structures on the blood flow in the model. The LV model at arbitrary time steps was constructed by deforming a computational mesh generated from MR images at a reference time step. The validity of the proposed construction scheme was confirmed by comparison with the configuration of an LV model extracted from MR images. Numerical analysis was performed for the unsteady blood flow in LV models with and without two simplified TC structures. The flow field in the model with the internal structure differed from that in the model without the internal structure near the wall, and flow separation caused by the internal structure decreased wall shear stress on the rear of the internal structure. The computational results provide fundamental information for the complex interaction between the internal structures and the blood flow in an LV.https://www.jstage.jst.go.jp/article/jbse/13/2/13_17-00597/_pdf/-char/enheart thrombusmagnetic resonance imagingcomputational fluid dynamicstrabeculae carneaewall shear stress |
spellingShingle | Tomomi YAMADA Toshiyuki HAYASE Suguru MIYAUCHI Kenichi FUNAMOTO Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images Journal of Biomechanical Science and Engineering heart thrombus magnetic resonance imaging computational fluid dynamics trabeculae carneae wall shear stress |
title | Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images |
title_full | Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images |
title_fullStr | Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images |
title_full_unstemmed | Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images |
title_short | Numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images |
title_sort | numerical analysis of the effect of trabeculae carneae models on blood flow in a left ventricle model constructed from magnetic resonance images |
topic | heart thrombus magnetic resonance imaging computational fluid dynamics trabeculae carneae wall shear stress |
url | https://www.jstage.jst.go.jp/article/jbse/13/2/13_17-00597/_pdf/-char/en |
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