Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge

Portal vein thrombosis (PVT), the second most common cause of portal hypertension, can be found in cirrhosis and non-cirrhosis patients. Various factors can cause non-cirrhosis PVT, such as biliary infection. Upper gastrointestinal bleeding without sign of liver failure, must be considered as non-ci...

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Main Authors: Syifa Mustika, Pratista Adi Krisna
Format: Article
Language:English
Published: Interna Publishing 2021-05-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Subjects:
Online Access:https://www.ina-jghe.com/index.php/jghe/article/view/778
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author Syifa Mustika
Pratista Adi Krisna
author_facet Syifa Mustika
Pratista Adi Krisna
author_sort Syifa Mustika
collection DOAJ
description Portal vein thrombosis (PVT), the second most common cause of portal hypertension, can be found in cirrhosis and non-cirrhosis patients. Various factors can cause non-cirrhosis PVT, such as biliary infection. Upper gastrointestinal bleeding without sign of liver failure, must be considered as non-cirrhosis PVT manifestation. Combining physical, laboratory, endoscopic and radiological examination is needed to establish the diagnosis of PVT. The principle of PVT management consists of 3 keypoints. They are prevention and treatment of gastrointestinal bleeding, prevention of recurrent thrombosis and portal cholangiopathy therapy. Many aspect should be considered regarding the administration of anticoagulants in PVT patients, especially chronic PVT with cavernomas.
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spelling doaj.art-ea33817e5d4b46548d1cda488f16dec02023-06-06T04:42:34ZengInterna PublishingThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy1411-48012302-81812021-05-01221798310.24871/221202179-83740Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic ChallengeSyifa Mustika0Pratista Adi Krisna1Division of Gastroentero-hepatology, Department of Internal Medicine, Faculty of Medicine, Brawijaya University/ Dr. Saiful Anwar General Hospital, MalangDepartment of Internal Medicine, Faculty of Medicine, Universitas Brawijaya/Dr. Saiful Anwar General Hospital, MalangPortal vein thrombosis (PVT), the second most common cause of portal hypertension, can be found in cirrhosis and non-cirrhosis patients. Various factors can cause non-cirrhosis PVT, such as biliary infection. Upper gastrointestinal bleeding without sign of liver failure, must be considered as non-cirrhosis PVT manifestation. Combining physical, laboratory, endoscopic and radiological examination is needed to establish the diagnosis of PVT. The principle of PVT management consists of 3 keypoints. They are prevention and treatment of gastrointestinal bleeding, prevention of recurrent thrombosis and portal cholangiopathy therapy. Many aspect should be considered regarding the administration of anticoagulants in PVT patients, especially chronic PVT with cavernomas.https://www.ina-jghe.com/index.php/jghe/article/view/778non cirrhosis portal vein thrombosisportal hypertensiongastrointestinal bleeding
spellingShingle Syifa Mustika
Pratista Adi Krisna
Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
non cirrhosis portal vein thrombosis
portal hypertension
gastrointestinal bleeding
title Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
title_full Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
title_fullStr Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
title_full_unstemmed Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
title_short Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge
title_sort non cirrhotic portal vein thrombosis diagnostic and therapeutic challenge
topic non cirrhosis portal vein thrombosis
portal hypertension
gastrointestinal bleeding
url https://www.ina-jghe.com/index.php/jghe/article/view/778
work_keys_str_mv AT syifamustika noncirrhoticportalveinthrombosisdiagnosticandtherapeuticchallenge
AT pratistaadikrisna noncirrhoticportalveinthrombosisdiagnosticandtherapeuticchallenge