Germline-competent stem cell in avian species and its application

Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent s...

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Main Authors: Jae Yong Han, Hyung Chul Lee, Tae Sub Park
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-06-01
Series:Asian Journal of Andrology
Subjects:
Online Access:http://ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=3;spage=421;epage=426;aulast=Han
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author Jae Yong Han
Hyung Chul Lee
Tae Sub Park
author_facet Jae Yong Han
Hyung Chul Lee
Tae Sub Park
author_sort Jae Yong Han
collection DOAJ
description Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds.
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spelling doaj.art-ea3522f53df4439894ffdcf2eb0964de2022-12-21T18:58:57ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622015-06-0117342142610.4103/1008-682X.148073Germline-competent stem cell in avian species and its applicationJae Yong Han Hyung Chul LeeTae Sub ParkGerm cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds.http://ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=3;spage=421;epage=426;aulast=Hanbirds; germline-competent stem cells; primordial germ cells; spermatogonial stem cells
spellingShingle Jae Yong Han
Hyung Chul Lee
Tae Sub Park
Germline-competent stem cell in avian species and its application
Asian Journal of Andrology
birds; germline-competent stem cells; primordial germ cells; spermatogonial stem cells
title Germline-competent stem cell in avian species and its application
title_full Germline-competent stem cell in avian species and its application
title_fullStr Germline-competent stem cell in avian species and its application
title_full_unstemmed Germline-competent stem cell in avian species and its application
title_short Germline-competent stem cell in avian species and its application
title_sort germline competent stem cell in avian species and its application
topic birds; germline-competent stem cells; primordial germ cells; spermatogonial stem cells
url http://ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=3;spage=421;epage=426;aulast=Han
work_keys_str_mv AT jaeyonghan germlinecompetentstemcellinavianspeciesanditsapplication
AT hyungchullee germlinecompetentstemcellinavianspeciesanditsapplication
AT taesubpark germlinecompetentstemcellinavianspeciesanditsapplication