Germline-competent stem cell in avian species and its application
Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent s...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2015-06-01
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Series: | Asian Journal of Andrology |
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Online Access: | http://ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=3;spage=421;epage=426;aulast=Han |
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author | Jae Yong Han Hyung Chul Lee Tae Sub Park |
author_facet | Jae Yong Han Hyung Chul Lee Tae Sub Park |
author_sort | Jae Yong Han |
collection | DOAJ |
description | Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds. |
first_indexed | 2024-12-21T15:24:40Z |
format | Article |
id | doaj.art-ea3522f53df4439894ffdcf2eb0964de |
institution | Directory Open Access Journal |
issn | 1008-682X 1745-7262 |
language | English |
last_indexed | 2024-12-21T15:24:40Z |
publishDate | 2015-06-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Asian Journal of Andrology |
spelling | doaj.art-ea3522f53df4439894ffdcf2eb0964de2022-12-21T18:58:57ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622015-06-0117342142610.4103/1008-682X.148073Germline-competent stem cell in avian species and its applicationJae Yong Han Hyung Chul LeeTae Sub ParkGerm cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds.http://ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=3;spage=421;epage=426;aulast=Hanbirds; germline-competent stem cells; primordial germ cells; spermatogonial stem cells |
spellingShingle | Jae Yong Han Hyung Chul Lee Tae Sub Park Germline-competent stem cell in avian species and its application Asian Journal of Andrology birds; germline-competent stem cells; primordial germ cells; spermatogonial stem cells |
title | Germline-competent stem cell in avian species and its application |
title_full | Germline-competent stem cell in avian species and its application |
title_fullStr | Germline-competent stem cell in avian species and its application |
title_full_unstemmed | Germline-competent stem cell in avian species and its application |
title_short | Germline-competent stem cell in avian species and its application |
title_sort | germline competent stem cell in avian species and its application |
topic | birds; germline-competent stem cells; primordial germ cells; spermatogonial stem cells |
url | http://ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=3;spage=421;epage=426;aulast=Han |
work_keys_str_mv | AT jaeyonghan germlinecompetentstemcellinavianspeciesanditsapplication AT hyungchullee germlinecompetentstemcellinavianspeciesanditsapplication AT taesubpark germlinecompetentstemcellinavianspeciesanditsapplication |