| Summary: | Thypoid fever is one of infection systemic disease cause by Salmonella enterica serotype typhi, this<br />bacterium is member of family Enterobacteriaciae. Everyone with thypoid fever bring the<br />bacterium in blood stream and gastrointestinal sytem so that it can transmit the infection to others<br />directly through water or food that has been contaminated. Laboratory examination to establish a<br />diagnosis of typhoid fever is with conventional methods, namely the culture of the bacterium and<br />serological test Widal and non-conventional method, namely Polimerase Chain Reaction (PCR),<br />Enzyme Immunoassay Dot (EID) and Enzyme-Linked Immunosorbent Assay (ELISA). The definitive<br />diagnosis of typhoid fever is with isolation of Salmonella enterica serotype typhi from blood, urine<br />or other body fluids. It is often not possible in developing countries because of inadequate<br />bakteriologik facilities on many small hospitals, while typhoid fever is an endemic disease in the<br />country. With this kind of situation, the diagnosis should be enforced by connecting the<br />corresponding clinical symptoms with typhoid fever and the presence of antibody titer is increasing<br />significantly in the blood against antigens O or H antigens of Salmonella enterica serotype typhi<br />(Widal test). <br />
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