Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer
Abstract Background About 5–10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women’s subjective valuation...
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-15568-0 |
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| author | Zahra Meshkani Najmeh Moradi Ali Aboutorabi Abdosaleh Jafari Roshanak Shams |
| author_facet | Zahra Meshkani Najmeh Moradi Ali Aboutorabi Abdosaleh Jafari Roshanak Shams |
| author_sort | Zahra Meshkani |
| collection | DOAJ |
| description | Abstract Background About 5–10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women’s subjective valuation for screening BRCA tests for early detection of breast cancer to help policymakers to make decisions about genetic screening tests for breast cancer and to know the applicants. Methods An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables. Results 660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP. Conclusions Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help. |
| first_indexed | 2024-04-09T17:44:25Z |
| format | Article |
| id | doaj.art-ea3b60132dd449eb859fa50fc687b75c |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-09T17:44:25Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-ea3b60132dd449eb859fa50fc687b75c2023-04-16T11:27:22ZengBMCBMC Public Health1471-24582023-04-012311910.1186/s12889-023-15568-0Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancerZahra Meshkani0Najmeh Moradi1Ali Aboutorabi2Abdosaleh Jafari3Roshanak Shams4Department of Health Economics, School of Health Management and Information Science, Iran University of Medical SciencesPopulation Health Sciences Institute, Newcastle UniversityDepartment of Health Economics, School of Health Management and Information Science, Iran University of Medical SciencesHealth Human Resources Research Center, School of health Management and Information Sciences, Shiraz University of Medical sciencesBone and Joint Reconstruction Research center, Department of Orthopedics, School of Medicine, Iran University of Medical SciencesAbstract Background About 5–10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women’s subjective valuation for screening BRCA tests for early detection of breast cancer to help policymakers to make decisions about genetic screening tests for breast cancer and to know the applicants. Methods An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables. Results 660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP. Conclusions Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help.https://doi.org/10.1186/s12889-023-15568-0Breast cancerGenetic screening testBRCAWillingness to pay (WTP)Iran |
| spellingShingle | Zahra Meshkani Najmeh Moradi Ali Aboutorabi Abdosaleh Jafari Roshanak Shams Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer BMC Public Health Breast cancer Genetic screening test BRCA Willingness to pay (WTP) Iran |
| title | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
| title_full | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
| title_fullStr | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
| title_full_unstemmed | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
| title_short | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
| title_sort | subjective valuation of iranian women for screening for gene related diseases a case of breast cancer |
| topic | Breast cancer Genetic screening test BRCA Willingness to pay (WTP) Iran |
| url | https://doi.org/10.1186/s12889-023-15568-0 |
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