The role of flavonoids in digestive tract cancer prevention - a review article
Introduction: Flavonoids are bioactive chemical compounds crucial for the functioning of plant organisms. Recently, they have been intensively studied in search of their potential application in medicine. One of the most popular fields in that regard is oncology. Digestive tract cancers are still a...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2023-06-01
|
| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/43873 |
| _version_ | 1797807143351484416 |
|---|---|
| author | Rafał Niemiec Justyna Branewska Barbara Ostrowska Mikołaj Matysek Anna Olszanicka Jan Imioło Anna Maciąg Izabela Hop Kacper Kołodziejczyk Adam Galas |
| author_facet | Rafał Niemiec Justyna Branewska Barbara Ostrowska Mikołaj Matysek Anna Olszanicka Jan Imioło Anna Maciąg Izabela Hop Kacper Kołodziejczyk Adam Galas |
| author_sort | Rafał Niemiec |
| collection | DOAJ |
| description | Introduction: Flavonoids are bioactive chemical compounds crucial for the functioning of plant organisms. Recently, they have been intensively studied in search of their potential application in medicine. One of the most popular fields in that regard is oncology. Digestive tract cancers are still a challenge for contemporary medicine. Our diet seems to have a direct impact on the etiology of colorectal, gastric, and esophageal cancers. The relationship between the consumption of flavonoids, their specific fractions, and digestive tract cancer morbidity is nowadays frequently investigated.
Purpose: This review article aims to discuss the most recent scientific reports and summarize the current state of knowledge, considering the role of flavonoids in digestive tract cancer prevention.
Materials and methods: Our work is based on articles accessed through medical information databases (Google Scholar, PubMed, CrossRef), various scientific books, and official NFZ and WHO-certified sites.
Results: Total flavonoid intake lowers gastric and esophageal cancer morbidity. A high amount of dietary catechins prevents the growth of gastric and colorectal cancer. Increased consumption of anthocyanidins, flavones, and flavanones decreases esophageal cancer morbidity. Isoflavones, procyanidines, anthocyanidins, flaonols, and flavones severely decrease the chance of developing colorectal cancer.
Conclusions: Flavonoids can play an important role in digestive tract cancer prevention. They suppress the growth of colorectal, gastric, and esophageal cancers. Nevertheless, new, high-quality studies are needed in order to compile adequate procedures and bring new, potential drugs to the market.
|
| first_indexed | 2024-03-13T06:18:07Z |
| format | Article |
| id | doaj.art-ea3cc772e42c4af4a4b0b6c9552d6c80 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-13T06:18:07Z |
| publishDate | 2023-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-ea3cc772e42c4af4a4b0b6c9552d6c802023-06-10T10:46:28ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-06-0137110.12775/JEHS.2023.37.01.003The role of flavonoids in digestive tract cancer prevention - a review articleRafał Niemiec0Justyna Branewska1Barbara Ostrowska2Mikołaj Matysek3Anna Olszanicka4Jan Imioło5Anna Maciąg6Izabela Hop7Kacper Kołodziejczyk8Adam Galas9Szpital Uniwersytecki w Krakowie ul. Kopernika 36 31-501Samodzielny Publiczny Wojewódzki Szpital Zespolony; Arkońska 4, 71-455 SzczecinUniwersytecki Szpital Kliniczny im. F. Chopina w Rzeszowie; Fryderyka Szopena 2, 35-055 RzeszówSzpital Miejski Specjalistyczny im. Gabriela Narutowicza w Krakowie; ul. Prądnicka 35-37, 31-202 KrakówSzpital Uniwersytecki w Krakowie ul. Kopernika 36 31-501 Szpital Specjalistyczny im. Stefana Żeromskiego SP ZOZ w Krakowie; Osiedle Na Skarpie 66, 31-913 KrakówCentrum Medyczne w Łańcucie SP. Z O.O. - Szpital Św. Michała Archanioła, ul. Ignacego Paderewskiego 5, 37-100 Łańcut 109 Szpital Wojskowy z Przychodnią SP ZOZ w Szczecinie; ul. Piotra Skargi 9-11, 70-965 Szczecin109 Szpital Wojskowy z Przychodnią SP ZOZ w Szczecinie; ul. Piotra Skargi 9-11, 70-965 SzczecinSzpital Uniwersytecki w Krakowie ul. Kopernika 36 31-501Introduction: Flavonoids are bioactive chemical compounds crucial for the functioning of plant organisms. Recently, they have been intensively studied in search of their potential application in medicine. One of the most popular fields in that regard is oncology. Digestive tract cancers are still a challenge for contemporary medicine. Our diet seems to have a direct impact on the etiology of colorectal, gastric, and esophageal cancers. The relationship between the consumption of flavonoids, their specific fractions, and digestive tract cancer morbidity is nowadays frequently investigated. Purpose: This review article aims to discuss the most recent scientific reports and summarize the current state of knowledge, considering the role of flavonoids in digestive tract cancer prevention. Materials and methods: Our work is based on articles accessed through medical information databases (Google Scholar, PubMed, CrossRef), various scientific books, and official NFZ and WHO-certified sites. Results: Total flavonoid intake lowers gastric and esophageal cancer morbidity. A high amount of dietary catechins prevents the growth of gastric and colorectal cancer. Increased consumption of anthocyanidins, flavones, and flavanones decreases esophageal cancer morbidity. Isoflavones, procyanidines, anthocyanidins, flaonols, and flavones severely decrease the chance of developing colorectal cancer. Conclusions: Flavonoids can play an important role in digestive tract cancer prevention. They suppress the growth of colorectal, gastric, and esophageal cancers. Nevertheless, new, high-quality studies are needed in order to compile adequate procedures and bring new, potential drugs to the market. https://apcz.umk.pl/JEHS/article/view/43873flavonoidsgastric cancer (GC)Esophageal cancerColorectal cancer |
| spellingShingle | Rafał Niemiec Justyna Branewska Barbara Ostrowska Mikołaj Matysek Anna Olszanicka Jan Imioło Anna Maciąg Izabela Hop Kacper Kołodziejczyk Adam Galas The role of flavonoids in digestive tract cancer prevention - a review article Journal of Education, Health and Sport flavonoids gastric cancer (GC) Esophageal cancer Colorectal cancer |
| title | The role of flavonoids in digestive tract cancer prevention - a review article |
| title_full | The role of flavonoids in digestive tract cancer prevention - a review article |
| title_fullStr | The role of flavonoids in digestive tract cancer prevention - a review article |
| title_full_unstemmed | The role of flavonoids in digestive tract cancer prevention - a review article |
| title_short | The role of flavonoids in digestive tract cancer prevention - a review article |
| title_sort | role of flavonoids in digestive tract cancer prevention a review article |
| topic | flavonoids gastric cancer (GC) Esophageal cancer Colorectal cancer |
| url | https://apcz.umk.pl/JEHS/article/view/43873 |
| work_keys_str_mv | AT rafałniemiec theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT justynabranewska theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT barbaraostrowska theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT mikołajmatysek theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT annaolszanicka theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT janimioło theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT annamaciag theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT izabelahop theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT kacperkołodziejczyk theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT adamgalas theroleofflavonoidsindigestivetractcancerpreventionareviewarticle AT rafałniemiec roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT justynabranewska roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT barbaraostrowska roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT mikołajmatysek roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT annaolszanicka roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT janimioło roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT annamaciag roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT izabelahop roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT kacperkołodziejczyk roleofflavonoidsindigestivetractcancerpreventionareviewarticle AT adamgalas roleofflavonoidsindigestivetractcancerpreventionareviewarticle |