Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis
Background: Hepatitis B virus infection is a major public health problem among pregnant women worldwide. Hepatitis B virus is highly infectious and is the most common cause of morbidity and mortality among pregnant women, and evidence is scarce on the pooled seroprevalence of hepatitis B virus in Et...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-03-01
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| Series: | Women's Health |
| Online Access: | https://doi.org/10.1177/17455057241235881 |
| _version_ | 1827325209173032960 |
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| author | Yordanos Sisay Asgedom Gizachew Ambaw Kassie Beshada Zerfu Woldegeorgis Mengistu Meskele Koyira Tsegaye Melaku Kebede |
| author_facet | Yordanos Sisay Asgedom Gizachew Ambaw Kassie Beshada Zerfu Woldegeorgis Mengistu Meskele Koyira Tsegaye Melaku Kebede |
| author_sort | Yordanos Sisay Asgedom |
| collection | DOAJ |
| description | Background: Hepatitis B virus infection is a major public health problem among pregnant women worldwide. Hepatitis B virus is highly infectious and is the most common cause of morbidity and mortality among pregnant women, and evidence is scarce on the pooled seroprevalence of hepatitis B virus in Ethiopia. Objectives: This study aimed to investigate the pooled seroprevalence of hepatitis B virus infection and factors associated with pregnant women in Ethiopia. Design: A systematic review and meta-analysis was employed in accordance with the Preferred Reporting Items for Systematic Reviews. Data sources: Searches were carried out in biomedical databases such as PubMed/Medline, Science Direct, Web of Science, Google Scholar, Hinari, and the Cochrane Library published in English until June 2023. Methods: Observational study designs were selected. Endnote citation manager was used to collect and organize the search outcomes and remove duplicate articles. The data were extracted using a Microsoft Excel spreadsheet and exported to STATA 16.0 software for the analysis. Results: A total of 48 research articles were included in the final analysis. The pooled estimated sero prevalence of hepatitis B virus infection among pregnant women in Ethiopia was 5.78% (95% confidence interval = 5.14, 6.43). History of abortion (odds ratio = 6.56, 95% confidence interval = 4.88, 8.90), history of blood transfusion (odds ratio = 5.74, 95% confidence interval = 4.04, 8.16), history of hospitalization (odds ratio = 5.40, 95% confidence interval = 3.68, 7.94), history of multiple sexual partner (odds ratio = 5.80, 95% confidence interval = 3.71, 9.05), history of surgical procedure (odds ratio = 7.39, 95% confidence interval = 4.16, 13.14), history of tattooing (odds ratio = 4.59, 95% confidence interval = 2.83, 7.43), and history of tooth extraction (odds ratio = 4.46, 95% confidence interval = 2.42, 8.22) were significantly associated with hepatitis B virus infection among pregnant women in Ethiopia. Conclusion: The overall pooled prevalence of hepatitis B virus infection among pregnant women in Ethiopia is relatively high. Having a history of abortion, blood transfusion, hospitalization, multiple sexual partners, surgical procedures, tattooing, and tooth extraction were found to be risk factors for hepatitis B virus. Therefore, extensive screening programs for hepatitis B virus in all pregnant women in Ethiopia are needed to prevent further infection and decrease the vertical transmission caused by the disease. Registration number: PROSPERO CRD: 42023438522 |
| first_indexed | 2024-03-07T14:18:54Z |
| format | Article |
| id | doaj.art-ea412afa8b944592ad51377d625b4f23 |
| institution | Directory Open Access Journal |
| issn | 1745-5065 |
| language | English |
| last_indexed | 2024-03-07T14:18:54Z |
| publishDate | 2024-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Women's Health |
| spelling | doaj.art-ea412afa8b944592ad51377d625b4f232024-03-06T10:04:34ZengSAGE PublishingWomen's Health1745-50652024-03-012010.1177/17455057241235881Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysisYordanos Sisay Asgedom0Gizachew Ambaw Kassie1Beshada Zerfu Woldegeorgis2Mengistu Meskele Koyira3Tsegaye Melaku Kebede4Department of Epidemiology, Wolaita Sodo University, Soddo, EthiopiaDepartment of Epidemiology, Wolaita Sodo University, Soddo, EthiopiaSchool of Medicine, Wolaita Sodo University, Soddo, EthiopiaSchool of Public Health, Wolaita Sodo University, Soddo, EthiopiaInstitute of Health, Jimma University, Jimma, EthiopiaBackground: Hepatitis B virus infection is a major public health problem among pregnant women worldwide. Hepatitis B virus is highly infectious and is the most common cause of morbidity and mortality among pregnant women, and evidence is scarce on the pooled seroprevalence of hepatitis B virus in Ethiopia. Objectives: This study aimed to investigate the pooled seroprevalence of hepatitis B virus infection and factors associated with pregnant women in Ethiopia. Design: A systematic review and meta-analysis was employed in accordance with the Preferred Reporting Items for Systematic Reviews. Data sources: Searches were carried out in biomedical databases such as PubMed/Medline, Science Direct, Web of Science, Google Scholar, Hinari, and the Cochrane Library published in English until June 2023. Methods: Observational study designs were selected. Endnote citation manager was used to collect and organize the search outcomes and remove duplicate articles. The data were extracted using a Microsoft Excel spreadsheet and exported to STATA 16.0 software for the analysis. Results: A total of 48 research articles were included in the final analysis. The pooled estimated sero prevalence of hepatitis B virus infection among pregnant women in Ethiopia was 5.78% (95% confidence interval = 5.14, 6.43). History of abortion (odds ratio = 6.56, 95% confidence interval = 4.88, 8.90), history of blood transfusion (odds ratio = 5.74, 95% confidence interval = 4.04, 8.16), history of hospitalization (odds ratio = 5.40, 95% confidence interval = 3.68, 7.94), history of multiple sexual partner (odds ratio = 5.80, 95% confidence interval = 3.71, 9.05), history of surgical procedure (odds ratio = 7.39, 95% confidence interval = 4.16, 13.14), history of tattooing (odds ratio = 4.59, 95% confidence interval = 2.83, 7.43), and history of tooth extraction (odds ratio = 4.46, 95% confidence interval = 2.42, 8.22) were significantly associated with hepatitis B virus infection among pregnant women in Ethiopia. Conclusion: The overall pooled prevalence of hepatitis B virus infection among pregnant women in Ethiopia is relatively high. Having a history of abortion, blood transfusion, hospitalization, multiple sexual partners, surgical procedures, tattooing, and tooth extraction were found to be risk factors for hepatitis B virus. Therefore, extensive screening programs for hepatitis B virus in all pregnant women in Ethiopia are needed to prevent further infection and decrease the vertical transmission caused by the disease. Registration number: PROSPERO CRD: 42023438522https://doi.org/10.1177/17455057241235881 |
| spellingShingle | Yordanos Sisay Asgedom Gizachew Ambaw Kassie Beshada Zerfu Woldegeorgis Mengistu Meskele Koyira Tsegaye Melaku Kebede Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis Women's Health |
| title | Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis |
| title_full | Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis |
| title_fullStr | Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis |
| title_full_unstemmed | Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis |
| title_short | Seroprevalence of hepatitis B virus infection and factors associated among pregnant women in Ethiopia: A systematic review and meta-analysis |
| title_sort | seroprevalence of hepatitis b virus infection and factors associated among pregnant women in ethiopia a systematic review and meta analysis |
| url | https://doi.org/10.1177/17455057241235881 |
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