A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma

Polyarteritis nodosa (PAN) is a medium-sized vessel vasculitis often presenting report as both stenotic and aneurysmal lesions. Association with antiphospholipid antibody (aPL) has also been described. Here, we reported a case of PAN with history of cutaneous vasculitis presenting as multiple territ...

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Main Author: Cheryl Chun Man Ng
Format: Article
Language:English
Published: World Scientific Publishing 2023-12-01
Series:Journal of Clinical Rheumatology and Immunology
Subjects:
Online Access:https://www.worldscientific.com/doi/10.1142/S2661341723720021
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author Cheryl Chun Man Ng
author_facet Cheryl Chun Man Ng
author_sort Cheryl Chun Man Ng
collection DOAJ
description Polyarteritis nodosa (PAN) is a medium-sized vessel vasculitis often presenting report as both stenotic and aneurysmal lesions. Association with antiphospholipid antibody (aPL) has also been described. Here, we reported a case of PAN with history of cutaneous vasculitis presenting as multiple territory ischemic stroke, mesenteric panniculitis, coronary artery stenosis on imaging; lupus anticoagulant (LA) was also identified, patient was treated with immunosuppressants and anticoagulation. Disease course was, however, complicated by development of thigh haematoma. Clinical manifestation of PAN and its association with aPL will be discussed.
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spelling doaj.art-ea482c02805140e5b56ada931b91aa192024-01-23T03:34:04ZengWorld Scientific PublishingJournal of Clinical Rheumatology and Immunology2661-34172661-34252023-12-012302798210.1142/S2661341723720021A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular HaematomaCheryl Chun Man Ng0Queen Elizabeth Hospital, Hong KongPolyarteritis nodosa (PAN) is a medium-sized vessel vasculitis often presenting report as both stenotic and aneurysmal lesions. Association with antiphospholipid antibody (aPL) has also been described. Here, we reported a case of PAN with history of cutaneous vasculitis presenting as multiple territory ischemic stroke, mesenteric panniculitis, coronary artery stenosis on imaging; lupus anticoagulant (LA) was also identified, patient was treated with immunosuppressants and anticoagulation. Disease course was, however, complicated by development of thigh haematoma. Clinical manifestation of PAN and its association with aPL will be discussed.https://www.worldscientific.com/doi/10.1142/S2661341723720021Polyarteritis NodosaIntramuscular HaematomaAntiphospholipid AntibodyVasculitis
spellingShingle Cheryl Chun Man Ng
A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma
Journal of Clinical Rheumatology and Immunology
Polyarteritis Nodosa
Intramuscular Haematoma
Antiphospholipid Antibody
Vasculitis
title A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma
title_full A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma
title_fullStr A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma
title_full_unstemmed A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma
title_short A Case of Polyarteritis Nodosa and Antiphospholipid Antibody Positivity Presenting with Intramuscular Haematoma
title_sort case of polyarteritis nodosa and antiphospholipid antibody positivity presenting with intramuscular haematoma
topic Polyarteritis Nodosa
Intramuscular Haematoma
Antiphospholipid Antibody
Vasculitis
url https://www.worldscientific.com/doi/10.1142/S2661341723720021
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