Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes

Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes

Three platinum complexes with cis and trans configuration cis-[Pt(TCEP)2Cl2], cis-[Pt(tmTCEP)2Cl2] and trans-[Pt(TCEP)2Cl2], where TCEP is tris(2-carboxyethyl)phosphine, have been synthesized and fully characterized by usual techniques including single-crystal X-ray diffraction for trans-[Pt(TCEP)2C...

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Bibliographic Details
Main Authors:	Marcelo Echeverri, Amparo Alvarez-Valdés, Francisco Navas, Josefina Perles, Isabel Sánchez-Pérez, A. G. Quiroga
Format:	Article
Language:	English
Published:	The Royal Society 2018-01-01
Series:	Royal Society Open Science
Subjects:	metallodrug–protein interaction cytotoxicity platinum drugs and dna
Online Access:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171340

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