Bilateral medial medullary infarction: three cases report and literatures review

Objective Bilateral medial medullary infarction (MMI) is prone to misdiagnosis. This study summarizes the clinical characteristics of MMI, in order to provide reference to clinicians. Methods and Results The clinical data of the 3 patients with acute bilateral MMI treated in Ruijin Hospital North Ca...

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Main Authors: FANG Rong, WU Bin, DENG Wei⁃ping, WANG Xiao⁃dan
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2022-06-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/2522
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author FANG Rong
WU Bin
DENG Wei⁃ping
WANG Xiao⁃dan
author_facet FANG Rong
WU Bin
DENG Wei⁃ping
WANG Xiao⁃dan
author_sort FANG Rong
collection DOAJ
description Objective Bilateral medial medullary infarction (MMI) is prone to misdiagnosis. This study summarizes the clinical characteristics of MMI, in order to provide reference to clinicians. Methods and Results The clinical data of the 3 patients with acute bilateral MMI treated in Ruijin Hospital North Campus affiliated to Shanghai Jiaotong University School of Medicine from January 2017 to January 2022 were collected. All 3 patients had acute onset, one case had acute myelitis⁃like manifestations (rapidly progressive quadriplegia), one case had intractable hiccup, and the other one had unilateral limb numbness and fatigue as the first manifestation, accompanied by hypoglossal palsy. The head MRI showed acute bilateral MMI (one case without acute lesions on early MRI). Two cases were misdiagnosed because of either presenting lower motor neuron damage signs or having atypical symptoms. All patients improved after antithrombotic therapy for acute cerebral infarction. Conclusions The clinical manifestations of acute bilateral MMI are diverse, and it's easy to be misdiagnosed in the early stage. The diagnosis is mainly based on clinical manifestations and head MRI, which requires early recognition and timely antithrombotic treatment for acute cerebral infarction. The main distinguishing points are whether there are risk factors for stroke, upper motor neuron damage signs, and the treatment was effective.
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spelling doaj.art-ea4adaa6f29a43df9f3c27dcf406e1d72022-12-22T00:32:33ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312022-06-0122651251810.3969/j.issn.1672⁃6731.2022.06.012Bilateral medial medullary infarction: three cases report and literatures reviewFANG Rong0WU Bin1DENG Wei⁃ping2WANG Xiao⁃dan3Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of MedicineDepartment of Neurology, Huashan Hospital, Fudan UniversityDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of MedicineDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of MedicineObjective Bilateral medial medullary infarction (MMI) is prone to misdiagnosis. This study summarizes the clinical characteristics of MMI, in order to provide reference to clinicians. Methods and Results The clinical data of the 3 patients with acute bilateral MMI treated in Ruijin Hospital North Campus affiliated to Shanghai Jiaotong University School of Medicine from January 2017 to January 2022 were collected. All 3 patients had acute onset, one case had acute myelitis⁃like manifestations (rapidly progressive quadriplegia), one case had intractable hiccup, and the other one had unilateral limb numbness and fatigue as the first manifestation, accompanied by hypoglossal palsy. The head MRI showed acute bilateral MMI (one case without acute lesions on early MRI). Two cases were misdiagnosed because of either presenting lower motor neuron damage signs or having atypical symptoms. All patients improved after antithrombotic therapy for acute cerebral infarction. Conclusions The clinical manifestations of acute bilateral MMI are diverse, and it's easy to be misdiagnosed in the early stage. The diagnosis is mainly based on clinical manifestations and head MRI, which requires early recognition and timely antithrombotic treatment for acute cerebral infarction. The main distinguishing points are whether there are risk factors for stroke, upper motor neuron damage signs, and the treatment was effective.http://www.cjcnn.org/index.php/cjcnn/article/view/2522medulla oblongatabrain infarctioncerebrovascular disorders
spellingShingle FANG Rong
WU Bin
DENG Wei⁃ping
WANG Xiao⁃dan
Bilateral medial medullary infarction: three cases report and literatures review
Chinese Journal of Contemporary Neurology and Neurosurgery
medulla oblongata
brain infarction
cerebrovascular disorders
title Bilateral medial medullary infarction: three cases report and literatures review
title_full Bilateral medial medullary infarction: three cases report and literatures review
title_fullStr Bilateral medial medullary infarction: three cases report and literatures review
title_full_unstemmed Bilateral medial medullary infarction: three cases report and literatures review
title_short Bilateral medial medullary infarction: three cases report and literatures review
title_sort bilateral medial medullary infarction three cases report and literatures review
topic medulla oblongata
brain infarction
cerebrovascular disorders
url http://www.cjcnn.org/index.php/cjcnn/article/view/2522
work_keys_str_mv AT fangrong bilateralmedialmedullaryinfarctionthreecasesreportandliteraturesreview
AT wubin bilateralmedialmedullaryinfarctionthreecasesreportandliteraturesreview
AT dengweiping bilateralmedialmedullaryinfarctionthreecasesreportandliteraturesreview
AT wangxiaodan bilateralmedialmedullaryinfarctionthreecasesreportandliteraturesreview