A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions
Purpose: Dry eye disease (DED) is because of a decrease in the tear film's volume or a change in the composition of tears. Evaporative dry eye is the most common type, which is due to meibomian gland dysfunction (MGD). In this study, the morphology of meibomian glands was evaluated in all kinds...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=4;spage=1420;epage=1425;aulast=Mounika |
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| author | Vala Mounika Sumana J Kamath Pagadala Tejaswi Ajay R Kamath Gladys R Rodrigues Teena Mariet Mendonca |
| author_facet | Vala Mounika Sumana J Kamath Pagadala Tejaswi Ajay R Kamath Gladys R Rodrigues Teena Mariet Mendonca |
| author_sort | Vala Mounika |
| collection | DOAJ |
| description | Purpose: Dry eye disease (DED) is because of a decrease in the tear film's volume or a change in the composition of tears. Evaporative dry eye is the most common type, which is due to meibomian gland dysfunction (MGD). In this study, the morphology of meibomian glands was evaluated in all kinds of dry eyes to look for any loss of meibomian glands, assess the function of remaining glands, and investigate the relationship between anatomy, function, and severity of DED. Methods: A total of 300 patients were included in the study, with 150 eyes in the study group and 150 in the control group. Meibomian gland morphology was assessed by examining the tarsal plate after everting the eyelids. Tear film function was evaluated using tear film break-up time (TBUT) and Schirmer's test (SCH I and II). Meibomian gland morphology was examined with a slit-lamp under magnification, a transilluminator using a small light emitting diode (LED) bulb, and non-contact meibography using an auto refracto-keratometer (ARK). Results: Females had a higher prevalence of dry eyes in our study. In all, 103 eyes (68.6%) in the study group had evaporative dry eye, making it the most prevalent type. Among the 150 controls, 104 controls with 69.3% had no dry eye symptoms, and in those with symptoms, the evaporative type was the most common, with a 28% prevalence. Conclusion: TBUT should be performed in all patients with detectable MG abnormality. Meibography has high specificity and sensitivity to diagnose MGD and in turn dry eyes and should be considered a routine screening modality. |
| first_indexed | 2024-03-13T10:36:32Z |
| format | Article |
| id | doaj.art-ea513c32be0b45349780cf86aaf72d47 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-03-13T10:36:32Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-ea513c32be0b45349780cf86aaf72d472023-05-18T05:50:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892023-01-017141420142510.4103/IJO.IJO_2823_22A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditionsVala MounikaSumana J KamathPagadala TejaswiAjay R KamathGladys R RodriguesTeena Mariet MendoncaPurpose: Dry eye disease (DED) is because of a decrease in the tear film's volume or a change in the composition of tears. Evaporative dry eye is the most common type, which is due to meibomian gland dysfunction (MGD). In this study, the morphology of meibomian glands was evaluated in all kinds of dry eyes to look for any loss of meibomian glands, assess the function of remaining glands, and investigate the relationship between anatomy, function, and severity of DED. Methods: A total of 300 patients were included in the study, with 150 eyes in the study group and 150 in the control group. Meibomian gland morphology was assessed by examining the tarsal plate after everting the eyelids. Tear film function was evaluated using tear film break-up time (TBUT) and Schirmer's test (SCH I and II). Meibomian gland morphology was examined with a slit-lamp under magnification, a transilluminator using a small light emitting diode (LED) bulb, and non-contact meibography using an auto refracto-keratometer (ARK). Results: Females had a higher prevalence of dry eyes in our study. In all, 103 eyes (68.6%) in the study group had evaporative dry eye, making it the most prevalent type. Among the 150 controls, 104 controls with 69.3% had no dry eye symptoms, and in those with symptoms, the evaporative type was the most common, with a 28% prevalence. Conclusion: TBUT should be performed in all patients with detectable MG abnormality. Meibography has high specificity and sensitivity to diagnose MGD and in turn dry eyes and should be considered a routine screening modality.http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=4;spage=1420;epage=1425;aulast=Mounikadry eyeevaporative dry eyemeibographymeibomian gland dysfunctionmeibomitisschirmer's testtear film break-up time |
| spellingShingle | Vala Mounika Sumana J Kamath Pagadala Tejaswi Ajay R Kamath Gladys R Rodrigues Teena Mariet Mendonca A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions Indian Journal of Ophthalmology dry eye evaporative dry eye meibography meibomian gland dysfunction meibomitis schirmer's test tear film break-up time |
| title | A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions |
| title_full | A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions |
| title_fullStr | A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions |
| title_full_unstemmed | A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions |
| title_short | A simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions |
| title_sort | simple technique of meibography for morphological and functional evaluation of meibomian glands in dry eye conditions |
| topic | dry eye evaporative dry eye meibography meibomian gland dysfunction meibomitis schirmer's test tear film break-up time |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=4;spage=1420;epage=1425;aulast=Mounika |
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