mTOR Signaling Pathway Regulates the Release of Proinflammatory Molecule CCL5 Implicated in the Pathogenesis of Autism Spectrum Disorder

mTOR Signaling Pathway Regulates the Release of Proinflammatory Molecule CCL5 Implicated in the Pathogenesis of Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a complex pervasive neurodevelopmental disorder and neuroinflammation may contribute to the pathogenesis of ASD. However, the exact mechanisms of abnormal release of proinflammatory mediators in ASD remain poorly understood. This study reports elevated plasma levels...

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Bibliographic Details
Main Authors: Baojiang Wang, Yueyuan Qin, Qunyan Wu, Xi Li, Dongying Xie, Zhongying Zhao, Shan Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
CCL5
autism spectrum disorder
NF-κB
mTOR
proinflammatory cytokines
neurodevelopmental disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.818518/full

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