The Effect of vitamin D on Eradication of Helicobacter Pylori

Background: Helicobacter Pylori (H.Pylori) is a very common bacterium infecting nearly half of population worldwide. Its eradication is related to multiple factors including host immune state and treatment regimens. Sufficient Serum Vitamin D may be associated with H. Pylori and its eradication rate...

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Bibliographic Details
Main Author: Bahzad Waso Hamad
Format: Article
Language:English
Published: university of basrah 2023-06-01
Series:Basrah Journal of Surgery
Subjects:
Online Access:https://www.iasj.net/iasj/download/116dc45fc5bb814a
Description
Summary:Background: Helicobacter Pylori (H.Pylori) is a very common bacterium infecting nearly half of population worldwide. Its eradication is related to multiple factors including host immune state and treatment regimens. Sufficient Serum Vitamin D may be associated with H. Pylori and its eradication rate. The aim of this study is to find any association of serum Vitamin D and H.Pylori eradication success rate .Patients and methods: 40 patients with upper gastrointestinal symptoms were involved in the study who were infected with Pylori and their urea breath were over 50 count per minute .They were treated by Levofloxacin-based triple therapy for 14 days, with estimation of their serum vitamin D. Re-testing done after 8 weeks to assess the success rate of eradication. Results: There was no association between serum level of vitamin D level and success rate of eradication as p value was 0.111. The eradication success rate was 54%. Conclusion: No association was found between serum vitamin D level and the eradication success rate of H. Pylori.
ISSN:1683-3589
2409-501X