Neoadjuvant therapy for locally advanced rectal cancer
By the beginning of the 2000s, oncologists have developed a standard algorithm for the management of patients with locally advanced rectal cancer. It includes preoperative chemoradiotherapy followed by surgery 6–8 weeks after chemoradiotherapy completion. However, there was no clear evidence indicat...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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“ABV-press” Publishing house”, LLC
2022-06-01
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| Series: | Тазовая хирургия и онкология |
| Subjects: | |
| Online Access: | https://ok.abvpress.ru/jour/article/view/536 |
| _version_ | 1797757075346948096 |
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| author | M. Yu. Fedyanin A. A. Tryakin |
| author_facet | M. Yu. Fedyanin A. A. Tryakin |
| author_sort | M. Yu. Fedyanin |
| collection | DOAJ |
| description | By the beginning of the 2000s, oncologists have developed a standard algorithm for the management of patients with locally advanced rectal cancer. It includes preoperative chemoradiotherapy followed by surgery 6–8 weeks after chemoradiotherapy completion. However, there was no clear evidence indicating the efficacy of adjuvant chemotherapy in this clinical situation. In recent decades, the concept of neoadjuvant treatment for locally advanced colon cancer changed due to an opportunity to perform hypofractionated radiotherapy and conduct chemotherapy in the preoperative stage. This literature review aims to summarize the results of studies analyzing neoadjuvant therapy for locally advanced colon cancer, as well as to compare the efficacy and tolerability of various therapeutic options currently available for this group of patients. |
| first_indexed | 2024-03-12T18:10:44Z |
| format | Article |
| id | doaj.art-ea58037143534a8e83217791b0503dfc |
| institution | Directory Open Access Journal |
| issn | 2686-9594 |
| language | Russian |
| last_indexed | 2024-03-12T18:10:44Z |
| publishDate | 2022-06-01 |
| publisher | “ABV-press” Publishing house”, LLC |
| record_format | Article |
| series | Тазовая хирургия и онкология |
| spelling | doaj.art-ea58037143534a8e83217791b0503dfc2023-08-02T09:16:19Zrus“ABV-press” Publishing house”, LLCТазовая хирургия и онкология2686-95942022-06-01122364510.17650/2686-9594-2022-12-2-36-45389Neoadjuvant therapy for locally advanced rectal cancerM. Yu. Fedyanin0A. A. Tryakin1N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaBy the beginning of the 2000s, oncologists have developed a standard algorithm for the management of patients with locally advanced rectal cancer. It includes preoperative chemoradiotherapy followed by surgery 6–8 weeks after chemoradiotherapy completion. However, there was no clear evidence indicating the efficacy of adjuvant chemotherapy in this clinical situation. In recent decades, the concept of neoadjuvant treatment for locally advanced colon cancer changed due to an opportunity to perform hypofractionated radiotherapy and conduct chemotherapy in the preoperative stage. This literature review aims to summarize the results of studies analyzing neoadjuvant therapy for locally advanced colon cancer, as well as to compare the efficacy and tolerability of various therapeutic options currently available for this group of patients.https://ok.abvpress.ru/jour/article/view/536rectal cancerneoadjuvant therapyradiotherapychemotherapy |
| spellingShingle | M. Yu. Fedyanin A. A. Tryakin Neoadjuvant therapy for locally advanced rectal cancer Тазовая хирургия и онкология rectal cancer neoadjuvant therapy radiotherapy chemotherapy |
| title | Neoadjuvant therapy for locally advanced rectal cancer |
| title_full | Neoadjuvant therapy for locally advanced rectal cancer |
| title_fullStr | Neoadjuvant therapy for locally advanced rectal cancer |
| title_full_unstemmed | Neoadjuvant therapy for locally advanced rectal cancer |
| title_short | Neoadjuvant therapy for locally advanced rectal cancer |
| title_sort | neoadjuvant therapy for locally advanced rectal cancer |
| topic | rectal cancer neoadjuvant therapy radiotherapy chemotherapy |
| url | https://ok.abvpress.ru/jour/article/view/536 |
| work_keys_str_mv | AT myufedyanin neoadjuvanttherapyforlocallyadvancedrectalcancer AT aatryakin neoadjuvanttherapyforlocallyadvancedrectalcancer |