EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA
Objective: In order to explore the nutritional and bioactive characteristics of the olive leaf, the study aimed to evaluate the biological potential of olive leaves by analyzing the effect of leaf extract on the glycemic and lipid profile of Wistar rats subjected to a hyperlipidic diet . Methodology...
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| Format: | Article |
| Language: | English |
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Universidade do Estado do Rio de Janeiro
2018-12-01
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| Series: | Demetra |
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| Online Access: | https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/37273 |
| _version_ | 1828746855696039936 |
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| author | Bruna da Fonseca Antunes Cristielle Aguzzi Cougo De Leon Alexandre Lorini Camila Castencio Nogueira Elizabete Helbig Rui Carlos Zambiazi |
| author_facet | Bruna da Fonseca Antunes Cristielle Aguzzi Cougo De Leon Alexandre Lorini Camila Castencio Nogueira Elizabete Helbig Rui Carlos Zambiazi |
| author_sort | Bruna da Fonseca Antunes |
| collection | DOAJ |
| description | Objective: In order to explore the nutritional and bioactive characteristics of the olive leaf, the study aimed to evaluate the biological potential of olive leaves by analyzing the effect of leaf extract on the glycemic and lipid profile of Wistar rats subjected to a hyperlipidic diet . Methodology: The experiment lasted 70 days; animals were divided and randomly distributed into 4 groups of 6 rats each, being N: normocaloric diet + water; H: hyperlipidic diet + water; NE: normocaloric diet + extract; and HE: hyperlipidic diet + extract. At the end of the experiment the effect of the aqueous extract of olive leaves on glycemia, lipid profile and lipid peroxidation were determined in rats. Results: The consumption of olive leaf extract by rats promoted changes in lipid profile and beneficial effect on the thiobarbituric acid reactive substances (TBARS) levels. Conclusions: Due to their chemical composition, rich in nutrients and compounds with bioactive properties, in addition to its considerable antioxidant and biological activities, olive leaves can be an option as a food supplement with biological properties.
DOI: 10.12957/demetra.2018.37273 |
| first_indexed | 2024-04-14T04:32:18Z |
| format | Article |
| id | doaj.art-ea588150c9ed468099d8a90c2cd2a00d |
| institution | Directory Open Access Journal |
| issn | 2238-913X |
| language | English |
| last_indexed | 2024-04-14T04:32:18Z |
| publishDate | 2018-12-01 |
| publisher | Universidade do Estado do Rio de Janeiro |
| record_format | Article |
| series | Demetra |
| spelling | doaj.art-ea588150c9ed468099d8a90c2cd2a00d2022-12-22T02:12:01ZengUniversidade do Estado do Rio de JaneiroDemetra2238-913X2018-12-011341041105510.12957/demetra.2018.3727321018EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICABruna da Fonseca Antunes0Cristielle Aguzzi Cougo De Leon1Alexandre Lorini2Camila Castencio Nogueira3Elizabete Helbig4Rui Carlos Zambiazi5Universidade Federal de PelotasUniversidade Federal de PelotasUniversidade Federal de PelotasUniversidade Federal de PelotasUniversidade Federal de PelotasUniversidade Federal de PelotasObjective: In order to explore the nutritional and bioactive characteristics of the olive leaf, the study aimed to evaluate the biological potential of olive leaves by analyzing the effect of leaf extract on the glycemic and lipid profile of Wistar rats subjected to a hyperlipidic diet . Methodology: The experiment lasted 70 days; animals were divided and randomly distributed into 4 groups of 6 rats each, being N: normocaloric diet + water; H: hyperlipidic diet + water; NE: normocaloric diet + extract; and HE: hyperlipidic diet + extract. At the end of the experiment the effect of the aqueous extract of olive leaves on glycemia, lipid profile and lipid peroxidation were determined in rats. Results: The consumption of olive leaf extract by rats promoted changes in lipid profile and beneficial effect on the thiobarbituric acid reactive substances (TBARS) levels. Conclusions: Due to their chemical composition, rich in nutrients and compounds with bioactive properties, in addition to its considerable antioxidant and biological activities, olive leaves can be an option as a food supplement with biological properties. DOI: 10.12957/demetra.2018.37273https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/37273oliveiraresíduo agroindustrialestresse oxidativoratos wistar. |
| spellingShingle | Bruna da Fonseca Antunes Cristielle Aguzzi Cougo De Leon Alexandre Lorini Camila Castencio Nogueira Elizabete Helbig Rui Carlos Zambiazi EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA Demetra oliveira resíduo agroindustrial estresse oxidativo ratos wistar. |
| title | EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA |
| title_full | EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA |
| title_fullStr | EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA |
| title_full_unstemmed | EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA |
| title_short | EFEITO BIOLÓGICO DO EXTRATO DE FOLHAS DE OLIVEIRA (OLEA EUROPAEA L.) EM RATOS SUBMETIDOS À DIETA HIPERLIPÍDICA |
| title_sort | efeito biologico do extrato de folhas de oliveira olea europaea l em ratos submetidos a dieta hiperlipidica |
| topic | oliveira resíduo agroindustrial estresse oxidativo ratos wistar. |
| url | https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/37273 |
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