Pulmonary aspergillosis: diagnosis and treatment
Aspergillus species are the most frequent cause of fungal infections of the lungs with a broad spectrum of clinical presentations including invasive pulmonary aspergillosis (IPA) and chronic pulmonary aspergillosis (CPA). IPA affects immunocompromised populations, which are increasing in number and...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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European Respiratory Society
2022-11-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/31/166/220114.full |
| _version_ | 1797961085485056000 |
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| author | Frederic Lamoth Thierry Calandra |
| author_facet | Frederic Lamoth Thierry Calandra |
| author_sort | Frederic Lamoth |
| collection | DOAJ |
| description | Aspergillus species are the most frequent cause of fungal infections of the lungs with a broad spectrum of clinical presentations including invasive pulmonary aspergillosis (IPA) and chronic pulmonary aspergillosis (CPA). IPA affects immunocompromised populations, which are increasing in number and diversity with the advent of novel anti-cancer therapies. Moreover, IPA has emerged as a complication of severe influenza and coronavirus disease 2019 in apparently immunocompetent hosts. CPA mainly affects patients with pre-existing lung lesions and is recognised increasingly frequently among patients with long-term survival following cure of tuberculosis or lung cancer. The diagnosis of pulmonary aspergillosis is complex as it relies on the presence of clinical, radiological and microbiological criteria, which differ according to the type of pulmonary aspergillosis (IPA or CPA) and the type of patient population. The management of pulmonary aspergillosis is complicated by the limited number of treatment options, drug interactions, adverse events and the emergence of antifungal resistance. |
| first_indexed | 2024-04-11T00:53:51Z |
| format | Article |
| id | doaj.art-ea5d6ecf49524c80a42073f067ea9109 |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-04-11T00:53:51Z |
| publishDate | 2022-11-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-ea5d6ecf49524c80a42073f067ea91092023-01-05T07:48:22ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172022-11-013116610.1183/16000617.0114-20220114-2022Pulmonary aspergillosis: diagnosis and treatmentFrederic Lamoth0Thierry Calandra1 Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland Aspergillus species are the most frequent cause of fungal infections of the lungs with a broad spectrum of clinical presentations including invasive pulmonary aspergillosis (IPA) and chronic pulmonary aspergillosis (CPA). IPA affects immunocompromised populations, which are increasing in number and diversity with the advent of novel anti-cancer therapies. Moreover, IPA has emerged as a complication of severe influenza and coronavirus disease 2019 in apparently immunocompetent hosts. CPA mainly affects patients with pre-existing lung lesions and is recognised increasingly frequently among patients with long-term survival following cure of tuberculosis or lung cancer. The diagnosis of pulmonary aspergillosis is complex as it relies on the presence of clinical, radiological and microbiological criteria, which differ according to the type of pulmonary aspergillosis (IPA or CPA) and the type of patient population. The management of pulmonary aspergillosis is complicated by the limited number of treatment options, drug interactions, adverse events and the emergence of antifungal resistance.http://err.ersjournals.com/content/31/166/220114.full |
| spellingShingle | Frederic Lamoth Thierry Calandra Pulmonary aspergillosis: diagnosis and treatment European Respiratory Review |
| title | Pulmonary aspergillosis: diagnosis and treatment |
| title_full | Pulmonary aspergillosis: diagnosis and treatment |
| title_fullStr | Pulmonary aspergillosis: diagnosis and treatment |
| title_full_unstemmed | Pulmonary aspergillosis: diagnosis and treatment |
| title_short | Pulmonary aspergillosis: diagnosis and treatment |
| title_sort | pulmonary aspergillosis diagnosis and treatment |
| url | http://err.ersjournals.com/content/31/166/220114.full |
| work_keys_str_mv | AT fredericlamoth pulmonaryaspergillosisdiagnosisandtreatment AT thierrycalandra pulmonaryaspergillosisdiagnosisandtreatment |