PK/PD modeling of Ceftiofur Sodium against Haemophilus parasuis infection in pigs

PK/PD modeling of Ceftiofur Sodium against Haemophilus parasuis infection in pigs

Abstract Background Ceftiofur Sodium is widely used in China. Our aim was to determine Ceftiofur Sodium activity and optimize dosing regimens against the pathogen Haemophilus parasuis using an in vitro and ex vivo pharmacokinetics/pharmacodynamics modeling approach. By adopting these strategies, we...

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Bibliographic Details
Main Authors: Xiao-dong Li, Sheng-Qing Chi, Li-Yun Wu, Can Liu, Tong Sun, Juan Hong, Xun Chen, Xiao-Gang Chen, Guan-Song Wang, Dao-Jin Yu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Veterinary Research
Subjects:
Ceftiofur sodium
Haemophilus parasuis
PK/PD model
Ex vivo bactericidal activity, Glässers disease
Online Access:http://link.springer.com/article/10.1186/s12917-019-2008-4

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